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Found 43 clinical trials
L Laura Thomas, MSc

Respiratory Support and Brain Health in Preterm Infants

Premature babies often require breathing support during their neonatal intensive care unit stay. This is because their lungs are not fully developed to perform the work of breathing on their own. Although breathing support can be provided via a breathing tube, it is preferable to provide breathing support non-invasively from …

3 years of age All Phase N/A

Kimel Family Centre for Brain Health and Wellness

Participants (n=450; aged 50+; without a diagnosis of dementia; sufficiently fluent in English to complete the assessments and engage in programming) receive a comprehensive dementia risk assessment, including nonmodifiable and modifiable risk factors, from which they receive a Personalized Dementia Risk Report and Program Strategy, indicating their health conditions increasing …

50 years of age All Phase N/A
L Lisa Haber-Chalom

Exercise to Improve Brain Health in Older African Americans

The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans. Specifically, the main question\[s\] it aims to answer are: What is the effect of a Cardio-Dance Fitness (CDF) vs. a Strength, Flexibility, and Balance …

60 years of age All Phase 2
R Research Services Professional

Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health

The purpose of this study is to learn more about how estradiol patch treatment affects brain processes, health, and wellbeing.

38 - 60 years of age Female Phase 4
K Kurečková Kurečková, Ing.

Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness

The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.

60 - 80 years of age All Phase N/A
B Barbara Ukropcova, Prof.

Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention

Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's disease. The aim of the study is to assess the impact of a supervised 9-month intervention with aerobic-strength training and nutritional counseling …

60 - 80 years of age All Phase N/A

Disentangling the Effect of Brain Insulin Resistance on Brain Health

People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition, persons with diabetes have more pronounced age-related brain atrophy and cognitive difficulties compared to people without diabetes. The mechanisms behind the effects on the brain of diabetes are still unclear. New research …

50 - 80 years of age All Phase N/A
A Annie J Roe, PhD

Trout Consumption in Young Children and Families and Brain Health

Regular fish consumption may support brain health. Trout lines developed in Idaho contain higher levels of omega-3 fatty acids, nutrients important for human cognition and mental wellbeing. Developed to support aquaculture sustainability, consumer preferences and human health benefits of these fish are unknown. The long-term goal of this project is …

3 years of age All Phase N/A
A Andrea Castillo, BS

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a previously clinically tested cognitive behavioral therapy for insomnia (CBT-I) mobile application paired with a wearable device (wrist actigraphy).

65 years of age All Phase N/A
D Douglas H Schultz, PhD

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults. The main questions it aims to answer are: Does eating more beef lead to higher scores on cognitive tests and better quality of life? Does …

19 - 24 years of age All Phase N/A

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