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Found 1,281 clinical trials
T Tatiana Khafif, Master's degree

ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder

The goal of this clinical trial is to test the efficacy of Acceptance and Commitment Therapy (ACT) as a psychotherapeutic treatment for patients with Bipolar Disorder (BD). The following questions will be investigated: The efficacy of ACT in reducing depressive symptoms in patients with BD. The efficacy of ACT in …

18 - 65 years of age All Phase N/A
X Xiaoming Du, PhD

Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia

The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia. Schizophrenia patients with depressive symptoms will be exposed to rTMS to improve their symptoms.

18 - 60 years of age All Phase N/A
K Katherine Scangos, MD, PhD

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Neurons are specialized types of cells that are responsible for carrying out the functions of the brain. Neurons communicate with electrical signals. In diseases such as major depression this electrical communication can go awry. One way to change brain function is using electrical stimulation to help alter the communication between …

22 - 70 years of age All Phase N/A

Improving Preschool Outcomes by Addressing Maternal Depression in Head Start

Within a research network of Head Start centers in Massachusetts, an efficacy trial of a stepped-care intervention (SCI) to address maternal depression, using intervention components that both prevent depression and help those in major depressive episode (MDE) engage with care, will be conducted. Both the prevention and engagement components of …

years of age Female Phase N/A
K Kirsten Penner-Goeke, MD

Feasibility and Acceptability of Group Medical Visits for Anxiety and Depression

The goal of this clinical trial is to evaluate the feasibility and acceptability of the intervention, Group Medical Visits (GMVs), for patients with depression and anxiety. It also aims to get some initial information on the effectiveness of GMVs on reducing depression and anxiety scores, which will help inform power …

18 years of age All Phase N/A
R Rosemary Smith, B.S.

Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder

Preliminary data have suggested that cannabidiol (CBD) may have a number of clinical benefits, including anti-anxiety and antidepressant properties. This study is a pilot open-label clinical trial assessing a custom-formulated high-CBD product over the course of 4 weeks in patients with bipolar disorder who experience anxiety.

18 - 55 years of age All Phase 2

The Half Swaddling Application on Infant Sleep Routine, Maternal Sleep Quality, Depression

In this prospective controlled study, it was aimed to examine the effects of half swaddling in term infants on infant sleep routine, maternal sleep quality and postpartum depression.

18 - 45 years of age Female Phase N/A
P Peizhen Zhang

Effects of Crossover Point Exercise on Depression, Anxiety and Stress in Chinese Postmenopausal Women

To analyze the effects of the Crossover Point (COP) Exercise Program on Chinese postmenopausal women.

45 - 70 years of age Female Phase N/A
f faculty of nursing H atta

Mindfulness-based Educational Intervention on Anxiety, Depression, Stress and Quality of Life on Menopausal Woman

Mindfulness-based educational intervention is a structured program that incorporates principles of mindfulness to help individuals develop greater awareness and acceptance of their thoughts, feelings, and bodily sensations. The intervention typically includes mindfulness meditation practices, cognitive-behavioral techniques, and educational components about stress management and emotional regulation. By fostering a non-judgmental and …

50 - 70 years of age Female Phase N/A
M Mona Kamal, Ph.D.

The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients

The study aims to investigate the effects of DPP-4 Is+ metformin versus SGLT2 Is + metformin on the risk of cognitive decline and depression in patients with T2DM.

55 years of age All Phase N/A

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