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Found 1,283 clinical trials
M Martha C Tompson, PhD

Neural Mechanisms of Family-Focused Treatment for Youth Depression

The goal of this interventional study is to compare the baseline neural mechanisms and parenting in depressed and non-depressed children and to examine baseline neural mechanisms and parenting as predictors of Family-Focused Treatment for Childhood-Depression (FFT-CD) outcomes. The main questions it aims to answer are: What are differences between depressed …

7 - 12 years of age All Phase N/A

Improving Preschool Outcomes by Addressing Maternal Depression in Head Start

Within a research network of Head Start centers in Massachusetts, an efficacy trial of a stepped-care intervention (SCI) to address maternal depression, using intervention components that both prevent depression and help those in major depressive episode (MDE) engage with care, will be conducted. Both the prevention and engagement components of …

years of age Female Phase N/A
K Katherine Scangos, MD, PhD

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Neurons are specialized types of cells that are responsible for carrying out the functions of the brain. Neurons communicate with electrical signals. In diseases such as major depression this electrical communication can go awry. One way to change brain function is using electrical stimulation to help alter the communication between …

22 - 70 years of age All Phase N/A

Effects of Booster Sessions on Depression Vulnerability Following Cognitive Control Training

The current study aims to examine the impact of booster sessions of cognitive control training (CCT) on indicators of depression vulnerability. Remitted depressed individuals (RMD) will be randomized over two groups, each receiving 10 sessions of the adaptive Paced Auditory Serial Addition Task, a well-established CCT procedure (Koster et al., …

18 - 65 years of age All Phase N/A
G Guus van den Brekel

Mechanisms of Change of Positive Interventions in Reducing Vulnerability for Depression

The purpose of this study is to understand the effects of mindfulness and fantasizing in reducing perseverative cognition underlying vulnerability for depression.

18 - 60 years of age All Phase N/A
K Kirsten Penner-Goeke, MD

Feasibility and Acceptability of Group Medical Visits for Anxiety and Depression

The goal of this clinical trial is to evaluate the feasibility and acceptability of the intervention, Group Medical Visits (GMVs), for patients with depression and anxiety. It also aims to get some initial information on the effectiveness of GMVs on reducing depression and anxiety scores, which will help inform power …

18 years of age All Phase N/A
R Rosemary Smith, B.S.

Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder

Preliminary data have suggested that cannabidiol (CBD) may have a number of clinical benefits, including anti-anxiety and antidepressant properties. This study is a pilot open-label clinical trial assessing a custom-formulated high-CBD product over the course of 4 weeks in patients with bipolar disorder who experience anxiety.

18 - 55 years of age All Phase 2

The Half Swaddling Application on Infant Sleep Routine, Maternal Sleep Quality, Depression

In this prospective controlled study, it was aimed to examine the effects of half swaddling in term infants on infant sleep routine, maternal sleep quality and postpartum depression.

18 - 45 years of age Female Phase N/A
P Peizhen Zhang

Effects of Crossover Point Exercise on Depression, Anxiety and Stress in Chinese Postmenopausal Women

To analyze the effects of the Crossover Point (COP) Exercise Program on Chinese postmenopausal women.

45 - 70 years of age Female Phase N/A
f faculty of nursing H atta

Mindfulness-based Educational Intervention on Anxiety, Depression, Stress and Quality of Life on Menopausal Woman

Mindfulness-based educational intervention is a structured program that incorporates principles of mindfulness to help individuals develop greater awareness and acceptance of their thoughts, feelings, and bodily sensations. The intervention typically includes mindfulness meditation practices, cognitive-behavioral techniques, and educational components about stress management and emotional regulation. By fostering a non-judgmental and …

50 - 70 years of age Female Phase N/A

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