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Found 65,447 clinical trials
S Shuxian Wu

High Definition Transcranial Direct Current Stimulation of Right Inferior Frontal Gyrus to Improve Social Impairments in Children with Autism

The goal of this clinical trial is to learn if high definition transcranial direct current stimulation (HD-tDCS) of right inferior frontal gyrus works to improve social impairments in children with autism spectrum disorder (ASD). It will also learn about the underlying brain mechanism. The main questions it aims to answer …

3 - 18 years of age All Phase N/A
J Jérôme Brunelin

Olfactory and Brain Stimulations in Treatment-resistant Depression

This is a prospective, randomized, double-blind, parallel-group controlled trial. The aim of this research project is to compare the clinical benefits achieved in patients with major depressive disorder (MDD) following two types of intervention: iTBS active alone or iTBS active combined with olfactory stimulations.

18 years of age All Phase N/A
P Pierre-Alexis DE NICE, MD

Evaluation of Anterior Tibial Knee Translation in Healthy Women With and Without Hormone Therapy

Women are recognized as being at greater risk of ACL injury, with a risk 6 times higher than that of men. Hyperlaxity is a risk factor for ACL injury, but the pathophysiological basis for this is poorly studied. Hormonal impregnation and certain periods of the menstrual cycle (ovulatory phase) are …

18 - 40 years of age Female Phase N/A
A Adam Lewkowitz, MD/MPHS

Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy

The goal of this randomized control trial is to assess if prenatal vaccine education and in-office vaccination administration for non-birthing partners of pregnant patients increases Tdap vaccination rates compared to usual care. The main question[s] it aims to answer are: To assess whether compared to standard prenatal care, targeted prenatal …

19 - 50 years of age All Phase 4

A Pilot Study to Evaluate the Efficacy and Safety of NaviFUS™ System Neuromodulating Treatment for Patients With Drug Resistant Epilepsy

This will be a prospective, pilot, open-label, two-arm, parallel-group, randomized study to evaluate the efficacy and safety of low-intensity focused ultrasound (LIFU) neuromodulation using NaviFUS System in patients with drug-resistant epilepsy (DRE).

18 - 65 years of age All Phase N/A

Safety and Effectiveness Evaluation of Spinal Laminectomy Robot

The purpose of this clinical trial is to evaluate the effectiveness and safety of this spinal robot in assisting doctors to perform laminectomy in spinal surgery under the premise of ensuring the safety of the subjects and ensuring the scientific nature of the clinical trial.

18 - 80 years of age All Phase N/A
K Kausik Chatterjee, FRCP, MD

The RETRAIN Trial Phase 2

Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom. This single-center prospective randomised study aims to measure cerebral blood flow and oxygen delivery in patients who have recently suffered an ischaemic stroke and are using …

18 years of age All Phase N/A

A Study of ONO-1110 in Patients With Social Anxiety Disorder

To Evaluate the Efficacy and Safety of ONO-1110 in Patients with Social Anxiety Disorder

18 - 65 years of age All Phase 2
N Ni Qihong, M.D.

Acostream Use in Patients With High Risk and Intermediate-risk Acute Pulmonary Embolism

The registry is to evaluate the safety and feasibility of catheter-directed aspiration for patients with high-risk and intermediate-high-risk pulmonary embolism using Acostream.

18 - 85 years of age All Phase N/A
D Dennis Kannenkeril, MD

Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation

The aim of this study is to observe the mechanisms of dapagliflozin on the renal interstitial tissue and renal perfusion. For this purpose, renal transplanted patients as an excellent model of CKD and high cardiovascular risk (similar to patients in DAPA-CKD study) are included in this study. The objectives of …

18 - 75 years of age All Phase 4

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