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Found 65,447 clinical trials
E Edith Martin, Ph.D

Evaluation of Trunk Assistance Exoskeleton

The goal of this interventional study is to evaluate the effect of three different designs of trunk assistance exoskeletons on cumulative lumbar load, trunk extensors' muscular fatigue and comfort in healthy volunteers. The main questions it aims to answer is: will exoskeletons reduce muscle fatigue and cumulative lumbar load. Participants …

18 - 65 years of age Male Phase N/A
A Angelo Marino, MD

Possible Action of Resveratrol in Improving the Outcomes of IVF/ICSI in Couples With Unexplained Infertility

Based on available evidence and given the potential beneficial effects of resveratrol in folliculogenesis and in oocyte development, the investigators designed a randomized, controlled, double-blind, single-center trial, whose objective will be the comparison of biological and clinical outcomes of resveratrol supplement in women undergoing IVF/ICSI cycles for unexplained infertility. To …

18 - 40 years of age Female Phase N/A
N Niels Thue Olsen, MD

The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

The objective of this study is to investigate, as a proof-of-principle, long-term (52 weeks) effects of tirzepatide once-weekly vs. placebo on changes in coronary plaque composition and progression (assessed by NIRS), plaque burden (assessed by IVUS) and microvascular function (assessed by invasively measured CFR) in overweight and obese individuals with …

18 years of age All Phase 4
D Devin McCarthy

Digital Art Therapy for Young Cancer Survivors

This is a single-site, single-arm, interventional study assessing the feasibility of the ARTCan Therapy Application (App) and whether it is an acceptable means of administering art therapy to young adult cancer survivors. The ARTCan Therapy App guides participants through a 6-week digital art therapy program. Subjects will participate in weekly …

18 - 25 years of age All Phase N/A
N Nihan Çakır Biçer, PhD.

Intermittent Fasting and Mediterranean Diet in Patient With Multiple Sclerosis

When the literature was reviewed, there is no study in which the effects of intermittent fasting and Mediterranean diet on quality of life, sleep, circadian rhythm and appetite hormones leptin and ghrelin levels in MS patients were evaluated and the two diet types were comparatively examined in terms of all …

18 - 65 years of age Female Phase N/A

tDCS and Spasticity in Stroke Patients

Multiple research has worked on tDCS and its impact on stroke. But none have studied the effects of tDCS on stroke in relation to the different stages of stroke like mild, moderate, moderate to severe and severe stroke as per national institute of health (NIH) scale. Additionally, this study will …

30 - 70 years of age All Phase N/A
S Stephanie Saunders, MA, CCRC

Lumateperone for the Improvement of Apathy in Patients With Psychotic Symptoms.

This study is looking to determine if Lumateperone improves motivation in patients with schizophrenia or schizoaffective disorders who show high levels of apathy as judged by AES-C-Apathy (Apathy Evaluation Scale - Clinician - Apathy) assessment and to examine a possible correlation between improvement in apathy scores and changes in elements …

18 - 65 years of age All Phase 3
C CRESCENT Research Staff

Clinical Research Evaluating Smoking Cessation With E-Cigarettes and Nicotine Therapy

This project will investigate the effects of alternative nicotine products on smoking, weight gain, and related outcomes.

21 years of age All Phase N/A
A Altay Kerimkulov, MD

Preventive Use of PIPAC in Locally Advanced Gastric Cancer.

Gastric cancer is the fifth most common cancer worldwide and the third leading cause of cancer-related mortality. In patients with locally advanced gastric cancer, multimodal treatment strategies, including perioperative chemotherapy, have significantly improved survival rates. Despite these advances, peritoneal carcinomatosis (PC) remains a serious problem, occurring in 60% of cases …

18 years of age All Phase N/A
C Clinical Trial Referral Office

5-strain Probiotic Formulation in HR-positive Breast Cancer Receiving Aromatase Inhibitor to Prevent Bone Loss

This phase II trial tests how well a probiotic, WBF-038, works in preventing bone loss in patients with early-stage hormone receptor-positive breast cancer who are starting treatment with aromatase inhibitors. Aromatase inhibitors are a drug that blocks the activity of an enzyme called aromatase, which the body uses to make …

18 years of age Female Phase 2

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