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Found 65,447 clinical trials
T Tiziana Lencioni

Improved Recovery of Walking in Acquired Muscle Weakness

The aim of Re-Walk-Easy is to evaluate the effects of rehabilitation based on electrical stimulation on the motor performance of critically ill patients. The study will also investigate the pathophysiology of the two forms-the myopathic-predominant and the polyneuropathic-predominant variants-by examining the longitudinal progression of CIP and CIM and determining which …

18 - 85 years of age All Phase N/A
N Nina Kimer, PhD

Optimized Remission in Alcohol-related Liver Cirrhosis

The incidence of liver cirrhosis is increased fivefold for men and tripled for women in the last forty years. The clinical course of liver cirrhosis includes complications of ascites, hepatic encephalopathy, variceal bleeding, kidney dysfunction, and infections that markedly worsen prognosis. These complications are driven by the development of portal …

18 years of age All Phase N/A
S Shankai Yin

Calcium Folinate Treatment of Spastic Paraplegia 56

SPG56 is one of the complicated and early-onset HSP subtypes caused by genetic mutations in CYP2U1. So far, there is no standardized and specific clinical therapy for SPG56. The goal of this clinical trial is to explore the efficacy and safety of calcium folinate in the treatment of SPG56 patients. …

years of age All Phase N/A
M Mette Cathrine Ørngreen, MD, DMSc

Whole Body Metabolism in Children With Cerebral Palsy With Low Skeletal Muscle Mass

At the center of pediatrics in Copenhagen the investigators experience that the children with CP with low skeletal muscle mass have more complications and admission after for example surgery is prolonged due to these complications. In order to prevent malnutrition and energy insufficiency as well as obesity and cardiometabolic disorders …

2 - 18 years of age All Phase N/A
J Jannatul Ferdoush Sumi, MBBS, MD Resident (phase B)

Effect of Vitamin D3 on Brain Waves in Male Parkinson's Patients With Low Vitamin D: A qEEG Study

This is an experimental study (Interventional self-controlled trial, pretest-posttest design). The goal of this clinical trial is to evaluate the effect of vitamin D3 supplementation on quantitative EEG in male Parkinson's disease patients with hypovitaminosis D. The main question it aims to answer is: Vitamin D3 supplementation has effect on …

51 - 70 years of age Male Phase N/A
I Ioannis G Fatouros, Prof

The Energy Cost of 1-Hour Football Training

This study aims at investigating the energy expenditure following a single Football trainning session in middle aged males. The participants will perform a soccer training session [A single training session including 60 minutes of warm up, soccer technical exercises and small-sided game] and a cotrol trial (No intervention included, only …

40 - 60 years of age Male Phase N/A
R Raymond Tong, PhD

Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network

Transcranial direct current stimulation (tDCS) has been applied to facilitate cortical excitability in stroke populations, as increasing evidence suggests that clinical recovery from stroke is attributed to neuroplastic reorganization. However, recovery from stroke following this kind of non-invasive neuromodulation remains divergent across stroke patients due to variations in their etiologies, …

years of age All Phase N/A
J Jianxin Wan, doctor

Multi-center Clinical Study on Hemoperfusion of KHA80

To evaluate the decreasing rate of blood IL-6, β2-MG and PTH in maintenance hemodialysis patients in the 52nd week compared with routine hemodialysis.

18 years of age All Phase N/A
Y Yuping Sun

Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors

The main purpose of this study is to evaluate the safety and tolerability of IBI3020 and to determine the maximum tolerated dose (MTD) and/or the recommended dose for expansion (RP2D) of IBI3020.

18 - 75 years of age All Phase 1
I Igor Utyashev, PhD

Feasibility Trial of Single-Dose Radiotherapy for Localized Low and Intermediate Risk Prostate Cancer

The goal of this study is to assess the feasibility of high-dose radiotherapy (Single-Dose Radiotherapy, SDRT) of 24 Gy in patients with localized low and intermediate risk prostate cancer using a special system of internal and external immobilization of the prostate gland. Patients eligible for this study are classified according …

18 years of age Male Phase N/A

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