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Found 65,447 clinical trials
M Morgane Ollivier, MD

Quality of Life and Quality of Sleep Studies in Children with Home Care Ventilation in the West of France

Home ventilation in children, invasive or non invasiv,e is an interesting treatment for different disease which cause chronic respiratory impairement. The aim of this treatment is to support alveolar hypoventilation. Concerned diseases are : neuro-muscular disease, upper airways pathologies, whest wall or lung pathologies, central control ventilation disease. Prevalence of …

6 - 17 years of age All Phase N/A

Positive Feeding of the Preterm Infant

The goal of this feasibility study is to assess the feasibility to implement a feeding strategy for preterm infants. The main questions it aims to answer are: Is it feasible to implement the PoP-intervention in a level 3a category Neonatal intensive care unit? Is the PoP-intervention acceptable for parents of …

years of age All Phase N/A
L Luke Lavallee, MDCM MSc FRCSC

VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy

Patients with genitourinary cancers (ex: bladder, testicular, kidney) are at high risk of developing blood clots if they receive systemic therapy (ex: chemotherapy, immunotherapy). Blood clots cause pain, may require hospitalization and invasive testing, and in some cases cause death. In fact, blood clots are one of the leading causes …

18 years of age All Phase 2/3
P Peng Wang, M.D.

Cryoablation Combined With Lenvatinib Plus Tislelizumab Compared With FOLFOX in Patients With Advanced Intrahepatic Cholangiocarcinoma (CASTLE-ZS-01)

This study will evaluate the efficacy and safety of cryoablation combined with lenvatinib plus Tislelizumab compared with FOLFOX in patients with advanced Intrahepatic Cholangiocarcinoma (ICC) who have progressed after first-line treatment.

18 years of age All Phase 2
Y Yanmin Zhao, PhD

Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study)

This is a prospective, multicenter, randomized controlled trial designed to evaluate the efficacy and safety of venetoclax-enhanced BUCY (Ven-BUCY) conditioning compared to the standard BUCY regimen in patients with high-risk acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). Eligible participants aged 12 to …

12 - 60 years of age All Phase N/A

Double-S: a Wearable Device for Erectile Dysfunction

The purpose of this study is to use a minimally invasive erectile device for patients suffering from erectile dysfunction.

18 years of age Male Phase N/A
F Fanming Kong, PhD

Electroacupuncture Combined With Immune Checkpoint Inhibitors as Adjuvant Therapy After Surgery for Early-stage Non-small Cell Lung Cancer

Postoperative immunoadjuvant therapy has been proven to significantly reduce the risk of recurrence after resectable NSCLC, and has become a new standard of postoperative adjuvant therapy for stage II-III NSCLC. Immunotherapy faces challenges such as immune resistance, heterogeneity of biomarker expression, and limitation of immune-suitable population. How to reduce the …

18 - 80 years of age All Phase 2/3
Q Qin Han

Efficacy and Safety of Photodynamic Therapy for Cervical and Vaginal Intraepithelial Neoplasia

To investigate the efficacy and safety of photodynamic therapy (20% 5-amino-ketovalerate 630nm red light) in the treatment of cervical and vaginal intraepithelial neoplasia in women in the real world.

18 - 65 years of age Female Phase N/A
C Caitlin S Sayegh, PhD

Health Care Transition Readiness Short-Form Video Intervention

The goal of this clinical trial is to assess whether social-media style short-form health education videos can increase health care transition readiness, self-efficacy, emotional well-being, health literacy, and appointment attendance, compared with publicly available health education resources in adolescents with chronic illnesses. The main question it aims to answer is: …

12 - 17 years of age All Phase N/A
A Aysima YALÇINTEPE

Marmet and Oxytocin Massage for Breast Milk Increase

This study is designed as a randomized controlled single-blind experimental study to examine the effectiveness of the oxytocin massage and Marmet technique applied to mothers who have undergone cesarean section on breast milk quantity and maternal state anxiety levels. The hypotheses of the study are as follows: H0.1. There is …

18 - 35 years of age Female Phase N/A

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