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Found 65,447 clinical trials
C Cristian Ichim, Resident Doctor

Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver Cirrhosis

The study aims to investigate the beneficial effects of fecal transplantation in patients diagnosed with liver cirrhosis (regardless of etiology).

18 years of age All Phase 3
C Cancer AnswerLine

Fezolinetant for the Improvement of Vasomotor Symptoms in Breast Cancer Patients Taking Endocrine Therapy, VENT Trial

This phase II trial tests how well fezolinetant works in improving vasomotor symptoms (VMS) in breast cancer patients taking endocrine therapy (ET). Anti-hormone treatments are effective for lowering the risk of breast cancer but can cause bothersome VMS, such as hot flashes and night sweats. Fezolinetant inhibits the activity of …

18 years of age Female Phase 2
R Rosario Ocampo, BSN

Pilot Trial Investigating Every Other Day Dosing of Oral Iron in Premature Infants (IQONic)

Study focuses on determining if daily versus every-other-day (EOD) oral iron at the same dose per kilogram per day will achieve similar incidence of iron replete status at 36 weeks post-menstrual age in premature neonates

26 - 32 years of age All Phase N/A
J J Coutinho, MD, PhD

Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance

Endovascular thrombectomy (EVT) is the standard treatment for large vessel occlusion (LVO) strokes, but it can only be performed in specialized hospitals. Since ambulance personnel cannot determine if a patient is eligible for EVT, 54% of LVO stroke patients are initially taken to non-EVT-capable hospitals, resulting in an average delay …

18 years of age All Phase N/A
A Anna Stanhewicz, PhD

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

The purpose of this investigation is to examine the mechanisms mediating vascular dysfunction in women who have had gestational diabetes and how metformin may be a valuable treatment tool to improve microvascular function in these women before the onset of disease.

18 - 45 years of age Female Phase N/A
M Marco D'Addario, PhD

Multi-domain Improvements in High-TEchnology Rehabilitation Programs for Post-stroke Patients

Through a multi-method, multi-informant, and patient-centred approach, the study aims to investigate the experience of use and the effectiveness of rehabilitation technology (robotics and virtual reality - VR) in post-stroke patients and their caregivers and therapists

18 years of age All Phase N/A
W Wenli Chen

Effectiveness of Harmonica Playing in Improving Lung Function Among COPD Patients

Although it has been documented that harmonica playing plays a role in the pulmonary rehabilitation (PR) of patients with chronic obstructive pulmonary disease (COPD), current studies are limited by small sample sizes, uncomprehensive outcome indicators, and short intervention durations. Thus, the investigators aim to compare the harmonica combination group with …

18 years of age All Phase N/A
X Xiaohua Wu, master

Study of Fruquintinib Plus Sintilimab for Treatment of Advanced Endometrial Cancer

The goal of this study is to evaluate whether fruquintinib(HMPL-013) plus sintilimab(IBI308) is safe and effective in the treatment of advanced endometrial cancer(EMC).

18 - 75 years of age Female Phase 3
L Lama Saad El-Din ED Mahmoud, PHD

Chitosan Phonophresis on Cervical IN Smartphone Addicted Users

A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored …

16 - 18 years of age All Phase N/A
H Hsueh-Chien Chiang

The Optimal Timing of the Initiation of Esophagogastroduodenoscopy After Oral Lidocaine Spray

Esophagogastroduodenoscopy (EGD) is the main examination in the upper gastrointestinal field. Aspiration pneumonia may happen if choking occurs during the EGD insertion, and the exam quality and efficacy may be affected if gag reflex occurs. The endoscopist may terminate the exam to avoid complications if the patient could not obey …

20 - 90 years of age All Phase N/A

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