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Found 44 clinical trials

Kimel Family Centre for Brain Health and Wellness

Participants (n=450; aged 50+; without a diagnosis of dementia; sufficiently fluent in English to complete the assessments and engage in programming) receive a comprehensive dementia risk assessment, including nonmodifiable and modifiable risk factors, from which they receive a Personalized Dementia Risk Report and Program Strategy, indicating their health conditions increasing …

50 years of age All Phase N/A
C Claudia M Lopez, BSc

PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health

This is a proof-of-concept phase 2 clinical trial to investigate the effect of the phytoestrogenic supplement PhytoSERM on vasomotor symptoms and other symptoms associated with the menopausal transition, and on blood-based biomarkers in peri- and postmenopausal women. After the screening period, participants will be randomized to PhytoSERM 50 mg pills …

45 - 60 years of age Female Phase 2
L Lisa Haber-Chalom

Exercise to Improve Brain Health in Older African Americans

The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans. Specifically, the main question[s] it aims to answer are: What is the effect of a Cardio-Dance Fitness (CDF) vs. a Strength, Flexibility, and Balance …

60 years of age All Phase 2
S Sandy Lwi, PhD

Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury

This study is testing the usefulness of two types of Brain Health & Wellness classes for Veterans with a history of concussion to improve mental health.

18 - 75 years of age All Phase N/A
K Kurečková Kurečková, Ing.

Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness

The study aims to evaluate the effects of a 9-month intervention combining yoga-based mindfulness techniques, cognitive training, and nutritional counseling on cognitive function, plasma markers of neurodegeneration (tau protein), physical fitness, and metabolism in older adults at increased risk of developing Alzheimer's disease.

60 - 80 years of age All Phase N/A
B Barbara Ukropcova, Prof.

Lifestyle for the BRAin Health - Nutrition and Exercise Training Intervention

Due to the increasing incidence of dementia and the lack of causal treatment, non-pharmacological interventions represent an attractive and effective therapeutic strategy of neurodegenerative diseases, such as Alzheimer's disease. The aim of the study is to assess the impact of a supervised 9-month intervention with aerobic-strength training and nutritional counseling …

60 - 80 years of age All Phase N/A
J Jenna Gardiner, BS

Trout Consumption in Young Children and Families and Brain Health

Regular fish consumption may support brain health. Trout lines developed in Idaho contain higher levels of omega-3 fatty acids, nutrients important for human cognition and mental wellbeing. Developed to support aquaculture sustainability, consumer preferences and human health benefits of these fish are unknown. The long-term goal of this project is …

3 years of age All Phase N/A
A Andrea Castillo, BS

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

The Sleep Optimization for Brain Health Outcomes in Older Surgical Patients (SLEEP-BOOST) is a pilot randomized, controlled, singled-blinded (participant) trial in major orthopedic joint surgery patients that will build on a previously clinically tested cognitive behavioral therapy for insomnia (CBT-I) mobile application paired with a wearable device (wrist actigraphy).

65 years of age All Phase N/A
D Douglas Schultz, PhD

Investigating the Effects of Beef Consumption on Cognitive and Brain Health

The goal of this clinical trial is to learn if eating more beef will lead to better cognition and a healthier brain in younger adults. The main questions it aims to answer are: Does eating more beef lead to higher scores on cognitive tests and better quality of life? Does …

19 - 24 years of age All Phase N/A
J June Lo, PhD

Personalising Children's Screen Use Reduction for Better Sleep, Mental, and Brain Health

In Singapore, 64.4% of school-age children sleep less than the minimum recommended duration of 9 hours on school nights, thus risking poor mental, cognitive, and brain health. These short-sleeping children, however, spend on average 2.5 hours per school day on non-academic media use, revealing the potential of reducing their screen …

6 - 12 years of age All Phase N/A

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