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Found 1,623 clinical trials
R Raquel García Álvarez

Registry of Patients in Shock Treated With Vasopressin

Arginine-vasopressin (AVP) is a non-catecholaminergic hormone produced in the hypothalamus and released into the circulation via the neurohypophysis. It has different actions depending on the receptors through which it acts: V1 (vasoconstriction, platelet aggregation, efferent arteriole constriction of the renal glomerulus, glycogenolysis); V2 (water reabsorption, release of von Willebrand factor …

18 years of age All Phase N/A
J John T Slevin, M.D., M.B.A.

A Causative Role for Amylin in Diabetic Peripheral Neuropathy

Three pieces of information lead to the basis for this study: Individuals with Type-2 diabetes commonly develop peripheral neuropathy. Increased production of the hormone amylin occurs in individuals who have Type-2 diabetes. Aggregations of amylin was found in the peripheral vasculature of rats that overexpressed human amylin. The purpose of …

18 years of age All Phase N/A
E Etienne Merlin

Host-microbiota-environment Interactions

Two types of inflammatory and autoimmune diseases (excluding monogenic diseases) can be distinguished in children: those similar to adult diseases but with an early onset (type 1 diabetes, inflammatory diseases of the gastrointestinal tract, rheumatoid arthritis with anti-CCP antibodies) and those specific to children that are not described in adults …

- 10 years of age All Phase N/A

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