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Found 1,604 clinical trials

24-hour Movement Behaviors Among Type 2 Diabetes Mellitus Patients

A healthy lifestyle has proved beneficial health effects in managing type 2 diabetes mellitus (T2DM). Important lifestyle behaviors, i.e. sleep, sedentary time (SB), and physical activity (PA) subdivided into light physical activity (LPA) and moderate to vigorous physical activity (MVPA), have shown an impact on T2DM disease-specific characteristics (e.g. glycemic …

18 - 100 years of age All Phase N/A
V Vaia Lambadiari, Professor

The Effect of Semaglutide on Cardiovascular Markers and Liver Function

Fifty patients with diabetes mellitus type 2 and non-alcoholic fatty liver disease (NAFLD) will be enrolled in the study. 25 patients will treated with semaglutide and 25 patients with dipeptidyl peptidase 4 (D-PP4) inhibitors. At baseline, at four and at 12 months will evaluate the endothelial, cardiovascular and liver function.

18 - 80 years of age All Phase N/A
S Stéphanie Cossec

Representation of Diet in the Management of Type 2 Diabetes in Migrant Patients at CHSD

This observational and monocentric study aims to explore how migrant patients with type 2 diabetes perceive and represent food in the context of their diabetes care. Conducted at the Centre Hospitalier de Saint-Denis, the study investigates the cultural, social, and personal factors that influence dietary habits and how these perceptions …

18 years of age All Phase N/A
H Hsiu-Chen Lin, PhD

Risk Factors for Developing Peak Plantar Pressure During Walking in the Diabetic Patients

The goal of this observational study is to investigate the clinically convenient dynamic and static measurement parameters to identify related risk factors of developing high peak plantar pressure during walking in the type-2 diabetic patients, and then establish a predictive model to estimate the likelihood of excessive plantar pressure. The …

18 years of age All Phase N/A

Movement Behaviours Among Bahraini Diabetics

This observational study aims to measure movement behaviours and explore factors influencing these among Bahraini patients with type 2 diabetes. The main objectives are: (i) Measure free-living physical activity and sedentary behaviour with an accelerometer device (ii) Examine associations between movement behaviours and anthropometric and diabetes-related biochemical/clinical parameters (iii) Examine …

20 - 75 years of age All Phase N/A
M Mette Pilegaard Rasmussen, BSc

The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin

The objective of the trial is to investigate the effect of adherence to oral semaglutide dosing instructions on glycaemic control in people with type 2 diabetes, which are dysregulated on metformin and naïve to second line antidiabetic treatment.

18 years of age All Phase N/A

Relationship Between Hemodynamic Changes and Cardiopulmonary Fitness in Type 2 Diabetes Mellitus Patients

Diabetes mellitus being metabolic disorder, chronic in nature, is characterized by high levels of glucose in our blood, which often lead to organ dysfunction. Approximately 10.5 % of adult (20-79 years) have diabetes according to international Diabetes federation. Cardiorespiratory fitness (CRF) is the capability of our cardiopulmonary system to make …

30 - 50 years of age All Phase N/A
E Elena Annoni, RN

Self-care Behaviors of Type 2 Diabetes Mellitus Patients

The goal of this observational study is to explore the experience of the chronic disease, with a particular focus on self-care, in adults with type 2 diabetes mellitus. The main questions it aims to answer are: what is the association between self-care and glycated hemoglobin over time? what are participants' …

18 years of age All Phase N/A
M Marti Boss, Msc

Visualizing Beta Cells After Bariatric Surgery

In order to evaluate the difference in beta cell mass in patients with and without complete resolution of type 2 diabetes mellitus (T2DM) after Roux en Y gastric bypass (RYGB) investigators aim to compare quantitative PET imaging of the pancreas between these patient groups. These highly relevant data will provide …

18 years of age All Phase N/A
Y Yenny Leal

Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

Cognitive disorders increase with age and in the presence of metabolic diseases such as Type 2 Diabetes Mellitus (T2DM). In addition, digestive disorders, changes in dietary pattern and decreased activity negatively influence the microbiome. The hypothesis is that pharmacological intervention with metformin will modify the composition of the gut microbiota …

65 - 80 years of age All Phase N/A

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