Advanced Filters
noise
Found 162 clinical trials
S Sarah Purcell, PhD

RMR Monitoring Feasibility and Acceptability

Obesity is a leading risk factor for chronic diseases such as type 2 diabetes, cancer, and cardiovascular disease. Generic weight management programs that target dietary intake and physical activity have been shown to be ineffective in maintaining weight loss beyond a 6-month period. Personalizing weight management programs produces more weight …

19 - 65 years of age All Phase N/A
A Amelia Brunani, MD

Metabolic Effects of a Diet Replaced With Essential Amino Acids

The effectiveness of low-protein diets supplemented with essential aminoacid (EAA) formulas in genetic disorders of amino acid (AA) catabolism, such as maple syrup urine disease (MSUD), is widely recognized (Blackburn PR et al. 2017). The main aim of the present study is to evaluate a difference in the effectiveness of …

45 - 65 years of age All Phase N/A
P Paula Aranaz, PhD

Effect of a Postbiotic Supplementation in Overweight and Obese Subjects: A Randomized Controlled Trial (PARABIOTICS-2).

The principal objective of this project is to evaluate the effect of a postbiotic supplement (inactivated microorganism) on body composition and other physiological and metabolic parameters related to excess body weight in overweight or obese adult men and women, as well as to determine changes in the gut microbiota associated …

18 - 70 years of age All Phase N/A

Use of Very Low Calorie Diet Preoperatively to Bariatric Surgery

To investigate use of Very Low Calorie Diet preoperatively to bariatric surgery can optimize weight loss prior to surgery and increase the patients' satisfaction.

18 - 65 years of age All Phase N/A
J Jennifer Gomez, MPH

Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes

The goal of this clinical trial is to evaluate the effectiveness of a 6-month lifestyle intervention compared to Metformin in postpartum women who have delivered a singleton, live born infant within the last 12 weeks to 1 year and had a pregnancy complicated by gestational diabetes. The main question this …

18 - 45 years of age Female Phase 2
J Jian Wang

Randomized Controlled Trial Evaluating Anti-Obesity Medications 6 Months After Metabolic Surgery

This clinical trial aims to evaluate the weight-loss efficacy and safety of efsubaglutide alfa in patients who remain obese 6 months after metabolic surgery.

18 - 55 years of age All Phase 4
J Jingyi Han, MD

The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males

Obesity, defined by WHO standards as having a body mass index (BMI) equal to or greater than 30 kg/m², affects approximately 800 million people worldwide. It is evident that obesity has become a serious public health issue, resulting in significant health burdens. Previous systematic reviews have indicated an association between …

22 - 40 years of age Male Phase N/A
J Justin Moore

Dyad Plus Effectiveness

The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase physical activity, healthy eating, and weight loss. Participants of the Brenner FIT (Families In Training) pediatric weight management …

13 - 65 years of age All Phase N/A
a ahmed MN Tolba, lecturer

Lifestyle Changes in Older Adults With Metabolic Syndrome and Tinnitus

The problem of tinnitus (subjective type) is prevalent in obese older adults with different diseases such as metabolic syndrome. The changes of lifestyle are very important to lose weight, improve tinnitus and metabolic syndrome

65 - 75 years of age All Phase N/A
L Lisa Tussing-Humphreys

Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers

Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically needed. This research will demonstrate that time-restricted eating, a type of intermittent fasting, is an effective therapy to …

45 - 70 years of age All Phase N/A

Simplify language using AI