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Found 1,595 clinical trials
S Surender, PhD

Effect of Oral Semaglutide on Liver Fat and Body Composition in Liver Transplant Recipients With Diabetes Mellitus

Nonalcoholic fatty liver disease (NAFLD) is a spectrum of liver conditions ranging from liver steatosis (NAFL), steatohepatitis (NASH), advanced liver fibrosis and ultimately leads to cirrhosis in a significant proportion of individuals. NAFLD is intimately associated with insulin resistance and associated disorders, such as obesity, type 2 diabetes, metabolic syndrome, …

30 years of age All Phase N/A
E Edward Jude, MD

Convenient Home Access for Routine Monitoring in Diabetes (Charm-D Study)

Diabetes mellitus is a global problem and regular monitoring of blood sugar control is important to reduce the risk of complications secondary to poor sugar control. To assess control a simple blood test is undertaken called the HbA1c. This test gives an assessment of the person's sugar control over the …

18 years of age All Phase N/A

Improving Glycemic Control With Telemedicine and Smart Insulin Pens

Almost 40% of veterans have diabetes, the proposed research may improve clinical care among veterans with diabetes. In this application we are going to examine whether utilizing Smart Insulin pens (SIPs) with CGMs and telemedicine is a better tool for managing diabetes compared to traditional insulin pens, CGMs and telemedicine, …

18 years of age All Phase N/A
K Kassiy Pierce

Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

Evaluation of Efficacy of Placental Membrane Dressings in Accelerating Diabetic Foot Healing

45 - 85 years of age All Phase 4
M Michelle Luk

Glucokinase Activator in Monogenic Diabetes

Evaluating a novel, allosteric glucokinase activator in monogenic diabetes secondary to inactivating glucokinase mutations: a randomised, cross-over trial

18 - 74 years of age All Phase 2
G Gan Zhou

A Clinical Study Comparing the Relative Bioavailability and Safety of SHR-3167 Injection

This study is a randomized, parallel, open-label Phase I clinical trial aimed at comparing the bioavailability and safety of different specifications of SHR-3167 injection, with healthy subjects as the research subjects.

18 - 55 years of age All Phase 1
A Adrian Dumitrascu, MD

Inpatient Use of Personal Continuous Glucose Monitor (CGM) to Improve Diabetes Mellitus Control

The purpose of this research is to prove that data generated by your real-time personal continuous glucose monitors CGMs brought in the hospital at the time of hospitalization can be monitored and safely used to guide insulin therapy aiming to improve glycemic control and to diminish the hypoglycemia and hyperglycemia …

18 years of age All Phase N/A
D Dr. Rubina Zulfqar

Pulsed Electromagnetic Field Therapy for Diabetic Foot Ulcer Sensation

Diabetes Mellitus (DM) is a chronic metabolic disorder characterized by hyperglycaemia for extended periods of time, which causes damage to peripheral nerves, resulting in sensory, motor and autonomic dysfunction. The study will aim to assess the effect of the Low pulse electromagnetic field therapy in VPT and protective sensation in …

40 - 60 years of age All Phase N/A
M María N Nachón, MD

Study of Adult Patients Residing in Argentina Diagnosed With Type 2 Diabetes Treated With a New Formulation of Semaglutide, Both Oral and Subcutaneous, in a Real-world Setting at 3 Months, 6 Months, and 1 Year of Follow-up, Quantifying the Reduction in Glycated Hemoglobin

The goal of this prospective, multicenter, observational study is to evaluate the real-world effectiveness and safety of oral and subcutaneous semaglutide in adults with type 2 diabetes mellitus in Argentina. The main objective is to assess changes in glycated hemoglobin (HbA1c) from baseline to 3, 6, and 12 months after …

18 years of age All Phase N/A
K Kerstin Kempf, PhD

AI Screening for Diabetic Retinopathy

The increasing prevalence of diabetes mellitus represents a major health problem, especially since around 40% of diabetic patients develop diabetic retinopathy, which severely impairs vision and can lead to blindness. This development could be prevented by annual check-ups and timely referral for treatment. However, there are major differences in the …

18 years of age All Phase N/A

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