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Belmont, Massachusetts Clinical Trials

A listing of Belmont, Massachusetts clinical trials actively recruiting patient volunteers.

Found 1,911 clinical trials

Digital Health Navigation for Latino Patients With Type II Diabetes

The goal of this clinical trial is to learn about digital literacy training in adult, Latino patient with type II diabetes. The main question it aims to answer is: Can providing digital literacy training during a hospital admission can help patients with their after-hospital care by using the patient portal …

18 years of age All Phase N/A
B Beatrice Hoffmann, MD

Hematoma Block for Distal Radius Fracture

The purpose of this study is to determine the efficacy of ultrasound guided hematoma block versus traditional "blind" hematoma block for analgesia in distal radius fracture reduction.

18 - 100 years of age All Phase N/A
P Pablo Sáinz-Ezquerra

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

This Phase 2a, multicenter, randomized, 12-week double-blind, placebo-controlled, parallel-group study, followed by an OLE, is designed to evaluate the safety, tolerability, and pharmacodynamic effects of BIIB122 in participants with LRRK2-PD. LRRK2-PD is defined as Parkinson's Disease (PD) in individuals who are heterozygous or homozygous carriers of a pathogenic LRRK2 variant …

30 years of age All Phase 2
C Cailey Tennyson, BA

Experiment 2: One Target in Many Situations

The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tasks are intermixed. Four search tasks are tested. The target is the same in every task but the types of distractors change from …

18 years of age All Phase N/A
Z Zeunab Kassem

Myo-inositol During Pregnancy to Prevent Gestational Diabetes

Myoinositol is an insulin-like compound that is present in both plant and animal cells. Humans synthesize it naturally, but it is also obtained in our diet. It works through an intracellular signaling pathway to increase insulin sensitivity. Myoinositol has been used as an over-the-counter (OTC) supplement in the management of …

18 - 45 years of age Female Phase N/A
M Michael Wagner, MD

BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma

This study is testing two different doses of BTX-A51 to determine if it is safe and tolerable in participants with liposarcoma with MDM2 amplification, myxoid liposarcoma, and CIC-rearranged sarcoma. The name of the study drug used in this research study is: -BTX-A51 (a type of kinase inhibitor)

18 years of age All Phase 1
F Freddrenia Holms

A Study of ONO-2020 in Participants With Mild to Moderate Alzheimer's Disease

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess safety, tolerability, pharmacokinetics, and efficacy of ONO-2020 in participants with mild to moderate Alzheimer's disease (AD). This study aims to determine whether administering ONO-2020, an epigenetic regulator, may improve cognitive functions like memory and cognition in individuals with Alzheimer's …

55 - 85 years of age All Phase 2
M Michele Reyen, MPH

Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC

The goal of this study is to conduct a pilot randomized waitlist-controlled trial to assess the feasibility, acceptability, and preliminary effects of substituting the NIDA standardized research e-cigarette (SREC) for combusted cigarettes in MOUD-TUD who are not ready to quit smoking. A waitlist controlled RCT using a mixed-methods sequential explanatory …

18 years of age All Phase N/A
S Sarah Richter

The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder

This open-label functional Magnetic Resonance Imaging (fMRI) study will assess the effects of a single dose of psilocybin on rumination and the neural correlates of rumination in individuals with major depressive disorder.

18 - 55 years of age All Phase 3
A Alexandra Touroutoglou, PhD

TMS for Cognitive Decline in Aging and Preclinical AD

In this research study we want to learn more about the effects of non-invasive brain stimulation on motivation, memory, and brain-network function in cognitively unimpaired older adults and individuals with preclinical Alzheimer's disease. This study will use a form of non-invasive brain stimulation called repetitive Transcranial Magnetic Stimulation (rTMS). rTMS …

40 - 99 years of age All Phase N/A

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