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Wigan, United Kingdom Clinical Trials

A listing of Wigan, United Kingdom clinical trials actively recruiting patients volunteers.

Found 30 clinical trials
K Klaus Hertting, MD

ALPHA LONG Study- BioMatrix AlphaTM Stent Study in Patients With CAD

Prospective, multi-center, open-label single-arm study designed to enroll 85 patients in up to 15 centers in up to 3 European countries. All patients will be followed up for 9 months. The "BMX Alpha Registry" study will serve as reference and historic comparator.

18 - 100 years of age Both Phase N/A
S Scot Garg

ULTRA LONG: BioFreedom Ultra

The goal of this Prospective, multi-center, open-label single-arm study is to Assess the Safety and Effectiveness of additional sizes of the BioFreedom Ultra CoCr Biolimus A9 coated coronary stent system in Patients at high risk of bleeding (HBR). The main question it aims to answer is to evaluate if the …

18 - 100 years of age Both Phase N/A
P Puneet Monga

Pyrocarbon Interposition Arthroplasty of the Elbow

The current study will be a prospective observational study (or collective case study in a small, carefully selected cohort of consenting patients with advanced arthritis. This study would be classified as a stage I study according the IDEAL framework for surgical innovation

18 - 60 years of age Both Phase N/A
L Lindsay Cunningham

Comparing Injection Treatments for Tennis Elbow

Tennis elbow is one of the most common musculoskeletal problems affecting the arm and is thought to be mainly due to overuse of the muscles that extend the wrist. The pain arises from the lateral epicondyle of the humerus, where the tendons of the wrist extensor muscles attach. There are …

18 - 75 years of age Both Phase N/A
R Raksha Mistry

Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)

Eligible patients with high risk colorectal malignancy (T3/4, spread greater than 5mm, EMVI positive) will have additional surveillance of breath hold T1, T2 and DW-MRIs (no IV contrast) post surgery six monthly for three years. Findings of liver MRIs as reported by radiology PI will be shared with their local …

16 - 100 years of age Both Phase N/A

The Role of Ixazomib in Autologous Stem Cell Transplant in Relapsed Myeloma - Myeloma XII (ACCoRd)

Study design: Randomised, controlled, multi-centre, open-label, phase III trial (with a single intervention registration phase). Primary Objectives The primary objectives of this study are to determine: The impact on Depth of Response (DoR: less than VGPR versus VGPR or better) when salvage ASCT conditioning is augmented by the addition of …

18 - 100 years of age Both Phase 3

Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom

This is a retrospective observational research study to describe the characteristics and real-world clinical outcomes of patients with chronic lymphocytic leukaemia receiving acalabrutinib in the United Kingdom (the EPIC study). Physicians treating chronic lymphocytic leukaemia patients with acalabrutinib, where the patients started treatment as part of the acalabrutinib Early Access …

18 - 130 years of age Both Phase N/A

Elbow Outcomes Clinical Study (WELBOW)

WELBOW study is an international, ambispective and prospective, single arm, multicenter, observational, non-comparative, Post-Market Clinical Follow-up (PMCF).

18 - 100 years of age Both Phase N/A
L Lorraine James

Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer

TRACC Part B This is a multi-centre, prospective, translational research study involving the collection and analysis of tumour tissue, serial blood samples and clinical data in patients with newly diagnosed stage I, II and III CRC. TRACC Part C is a : (multi-centre, prospective, randomised study, of ctDNA guided adjuvant …

18 - 100 years of age Both Phase N/A
P Puneet Monga

Superior Capsular Reconstruction With InternalBrace Study

The aim of the study is to investigate the clinical and radiological outcomes after superior capsular reconstruction with InternalBrace (SCRIB) performed for irreparable rotator cuff tears.

18 - 80 years of age Both Phase N/A

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