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Newcastle upon Tyne, United Kingdom Clinical Trials

A listing of Newcastle upon Tyne, United Kingdom clinical trials actively recruiting patients volunteers.

Found 139 clinical trials
R Registry Project Manager and Curator

The United Kingdom National Registry for Myotonic Dystrophy

Myotonic dystrophy (dystrophia myotonica - DM) exists in two forms, usually referred to as DM1 (type 1) and DM2 (type 2). Both conditions are genetic disorders but each affects a different gene. DM1 is the most common adult-onset muscular dystrophy, and is thought to affect at least 1 in 8,000 …

years of age All Phase N/A

Mobilise-D: Extension Study

The goal of this observational study is to investigate the ability of a mobility monitor to measure and predict outcomes in Parkinson's disease (PD). It is an extension of a previous study (the Mobilise-D Clinical Validation Study) and consists of an additional follow-up visit for PD participants and the recruitment …

18 years of age All Phase N/A
S Sarah Charman

Lifestyle Behaviours of Women Newly Diagnosed With Heart Failure

Heart Failure occurs when the heart's ability to pump blood is reduced. Heart failure can lead to symptoms of breathlessness, fatigue and ankle swelling, and result in health complications including damage to other organs (e.g. kidneys), reduced function and quality of life. Although the symptoms of heart failure are similar …

18 years of age Female Phase N/A
L Lily Robinson

Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

NIMBLE is a prospective study for blood biomarker study of lung nodules alongside analysing data which has been collected routinely as part of patient care. The primary aim of NIMBLE is to assess whether artificial intelligence and machine learning based radiomics approaches can be used to distinguish between benign disease …

18 years of age All Phase N/A
R Ruth DaSilva

Visual Perception Difficulties After Stroke

The goal of this observational study is to learn how well the Oxford Visual Perception Screening (OxVPS) tool can identify stroke survivors with visual perception difficulties. The main aim is to determine the accuracy and utility of the OxVPS compared to the current gold standard assessment in stroke survivors. In …

18 years of age All Phase N/A
R Richard Walker

Ocular Microtremor in Parkinson's Disease.

This is an exploratory, observational study that will use a novel handheld device - The iTremor ONE, which has been developed to rapidly, non-invasively assess and evaluate OMT frequency. This device uses incident laser technology directed at the sclera. PwPD who meet the inclusion criteria will participate in a home-based …

18 years of age All Phase N/A

Micro-EMG: A Novel Multi-electrode System for Intramuscular Imaging

The purpose of this small-scale exploratory study is to bridge the knowledge gap between the bench testing and the design of potential future confirmative studies. Identifying and evaluating MicroEMG measurement parameters in this exploratory manner is a necessary step to evaluate its usability and design, and determine whether the microEMG …

18 years of age All Phase N/A
P Peter Ireland, MBBS

Eosinopenia in Severe COPD Exacerbation

The goals of this observational study are to identify factors independently associated with admission eosinopenia in patients with a severe exacerbation of chronic obstructive pulmonary disease (COPD) and to determine when blood eosinophil count (BEC) will recover to baseline stable state in patients who are admitted to hospital with a …

35 years of age All Phase N/A
T The Chief Investigator

ICONIC: Improving Outcomes Through Collaboration in OsteosarComa

There has been little improvement in outcome for patients with osteosarcoma (OS) over the last 20 years. There have been only a few clinical trials of new treatments and no major new therapies introduced recently. This is in part because there is no good understanding of the biology of osteosarcoma, …

years of age All Phase N/A

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