Advanced Filters
noise

Isleworth, United Kingdom Clinical Trials

A listing of Isleworth, United Kingdom clinical trials actively recruiting patients volunteers.

Found 721 clinical trials
N Neeraj Shah

Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure

To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.

18 years of age All Phase N/A
O Oliver J Robinson, PhD

CBT and the Neural Circuits of Anxiety

This study will aim to test whether specific neural circuitry changes, proposed on the basis of a neurocognitive model of anxiety, are a mechanism of action for Cognitive Behavioural Therapy (CBT) interventions. This study aims to provide a theoretical model of the neurobiological mechanisms of CBT's therapeutic effect, where there …

18 - 64 years of age All Phase N/A
B Ben O'Leary

ORganoid GeneratioN Study for Cancer

ORIGINS - a multi-site sample collection study to establish patient-derived pre-clinical models for cancers

18 years of age All Phase N/A
P Peter O'Kane

Finding the Invasive Haemodynamic Threshold for Symptom Relief in Stable Angina

ORBITA-FIRE is a randomised, double-blinded, placebo controlled experimental study that will identify the fractional flow reserve (FFR) and non-hyperemic pressure ratio (NHPR) thresholds that correlate with symptoms of angina for 58 patients measured invasively under experimental conditions.

18 years of age All Phase N/A
J John Ho, FRCPCH

Fathers and Partners in Family Integrated Care Study

AIMS: The primary aim is to investigate the impact of enhancing father/partner engagement in FICare of preterm infants on their mental health (MH) up to 6 weeks post discharge. Secondary aims are to investigate the impact on maternal MH. METHOD and ANALYSIS: This is a two-phase study: Phase-1 to gather …

years of age All Phase N/A
T Tricia Seow, PhD

Neural Mechanisms of Obsessive-compulsive Disorder (OCD) Treatment Failure

The aim of this study is to understand why patients with obsessive-compulsive disorder (OCD) fail in therapy. To understand the neural mechanisms involved in exposure therapy that support success and clinical improvement in order to improve therapy outcomes for OCD patients.

18 - 55 years of age All Phase N/A
S Sunder Chita

High Frame Rate Ultrasound in Heart Disease Assessment

The study will compare standard ultrasound images to high frame rate ultrasound images in patients with heart disease or with a low risk of heart disease to see if a higher frame rate of ultrasound adds to the information obtained from standard ultrasound.

18 years of age All Phase N/A
L Lily Robinson

Nodule IMmunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

NIMBLE is a prospective study for blood biomarker study of lung nodules alongside analysing data which has been collected routinely as part of patient care. The primary aim of NIMBLE is to assess whether artificial intelligence and machine learning based radiomics approaches can be used to distinguish between benign disease …

18 years of age All Phase N/A
C Cordelia Grant

Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been completed within 6 weeks prior to surgery. Two x 20ml blood samples will be taken from each patient, one prior to and …

16 years of age All Phase N/A
K Karina Tukanova, MD

Oesophagectomy and Chest Wall and Respiratory Function

Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%). Minimally invasive approach through keyhole surgery has been shown to reduce pulmonary infections by 20%. Enhanced recovery programmes are evidence-based protocols, developed to achieve early recovery after surgery with …

18 - 90 years of age All Phase N/A

Simplify language using AI