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Croydon, United Kingdom Clinical Trials

A listing of Croydon, United Kingdom clinical trials actively recruiting patients volunteers.

Found 800 clinical trials
S Sarah Cannon Research Institute

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

This is an open-label, Phase 1/2 study to determine the safety, tolerability, and efficacy of APL-4098 alone and/or in combination with azacitidine for the treatment of relapsed or refractory (R/R) acute myeloid leukemia (AML), myelodysplastic syndrome (MDS)/AML and MDS-excess blasts (EB). Participants with the MDS-EB subtype will be eligible for …

18 years of age All Phase 1/2
S Syed Ahsan

Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation

A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).

18 - 80 years of age All Phase N/A
S Steven Masson

A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis

A feasibility trial called PROFIT has previously shown that FMT administered endoscopically into the jejunum in patients with cirrhosis is safe and feasible and have identified some potential mechanisms of action that warrant further interrogation. The aim of the PROMISE Trial is to evaluate the efficacy and mechanisms of action …

18 years of age All Phase 3

Zanubrutinib Plus Rituximab for Patients With Indolent Mantle Cell Lymphoma

Phase II, multicentre, randomised, open-label study to assess the benefit of early intervention with fixed duration, time-limited zanubrutinib-rituximab in indolent mantle cell lymphoma (MCL)

18 years of age All Phase 2
A Aida Suarez-Gonzalez, Dr

BELIDE: Better Living With Non-memory-led Dementia

Around 48 million people worldwide 1 live with dementia, of whom 3.9 million start with symptoms before the age of 65 (young-onset dementia). Most of the people presenting with young-onset dementia and some people with later onset dementia develop non-memory led dementias such as the atypical forms of Alzheimer ́s …

18 years of age All Phase N/A

A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of a single dose of ALN-HTT02.

25 - 70 years of age All Phase 1
M Mat Lister

Relationships in Good Hands - Clinical and Cost-effectiveness of Dyadic Developmental Psychotherapy

The research question is: Can the research recommend better ways for social care and health services to work work together to help adoptive and foster families? Can a therapy called DDP improve the mental health of 5-12 year old fostered or adopted children? Is DDP worth the commitment families need …

5 - 12 years of age All Phase N/A
A Aldo Rinaldi

Rate or Rhythm Control in CRT: the RHYTHMIC Study

70 patients with heart failure, AF and CRT with BiV<95% will be randomised to either AF ablation or AV node ablation. Evaluation at 6 months with echocardiography and clinical assessment.

18 - 85 years of age All Phase N/A
C Cassie Hazell

UniVRse: VR-CBT for Students With Social Anxiety

The goal of this pilot randomised controlled trial is to evaluate the effectiveness of the UniVRse VR-CBT programme in students with social anxiety. The aims of this trial are: To determine whether a full trial is justified; To establish the effect size on the co-primary outcomes for a sample size …

18 years of age All Phase N/A
P Preeti Kaur Khurana, MSc

TRANS-FOODS: Preventing Peanut Allergy Through Improved Understanding of the Transcutaneous Sensitisation Route, Novel Food Processing and Skin Care Adaptations

This project aims to study the immune responses to peanut allergen in those with a skin barrier defect with and without skin massage, specifically it aims to: Establish if peanut allergen components can pass into human skin through regular massage using the peanut protein-containing extract. Clarify whether this effect is …

18 - 65 years of age All Phase N/A

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