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Carshalton, United Kingdom Clinical Trials

A listing of Carshalton, United Kingdom clinical trials actively recruiting patients volunteers.

Found 554 clinical trials
K Kendra Shaw

Brief Intervention for FCD: A Feasibility Study

The goal of this study is to learn if a single session intervention for people with Functional Cognitive Disorder (FCD) is feasible and acceptable. The main questions it aims to answer are: What is the impact of a single session intervention on FCD symptoms, functional impairment, and quality of life …

18 - 65 years of age All Phase N/A
R Ramya Ramanujachar

A Multi-Arm, Platform Trial For Relapsed Neuroblastoma

Neuroblastoma is one of the most common solid childhood tumours, and a major cause of cancer-related death in children. More than 1200 children/young adults a year are diagnosed in USA and Europe. Around 600 of these cases are considered high-risk, which means the cancer is more difficult to treat successfully. …

1 years of age All Phase 1/2
L Lalantha Leelarathna, PhD FRCP

Automated Insulin Delivery in Adults With Advanced Kidney Disease

Diabetes is the leading cause of kidney failure in the UK. Many people with diabetes and advanced kidney failure inject themselves with insulin and do finger-prick blood glucose tests. Managing diabetes in people with advanced kidney disease is hard, with fluctuating glucose levels and an increased risk of unsafe low …

18 - 70 years of age All Phase N/A
A Aislinn Bowler, PhD

ADHD Remote Technology and ADHD Transition: Predicting and Preventing Negative Outcomes

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition affecting 5.9% of young people. Late adolescence can be a particularly challenging period for young people with ADHD, with major life transitions, new demands and increased expectations. This vulnerable phase also coincides with the transition from child and adolescent mental …

16 - 17 years of age All Phase N/A

Test-retest Study With [18F]FBB in Cardiac Amyloidosis

This study is an open-label study to evaluate and characterize test-retest reliability of \[18F\]florbetaben PET in subjects with AL-CA and ATTR-CA compared to non-CA subjects. Quantification of the \[18F\]florbetaben parameters related to the deposition of amyloid in the heart (such as Myocardial Tracer Retention (MTR) or Retention Index (RI)), and …

40 years of age All Phase 1

A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure

The study is testing a new drug (NNC0537-1482) to potentially treat people with heart failure. The purpose of the study is to see if NNC0537-1482 is safe and how it works in the body. Participants will either get NNC0537-1482 or placebo (a "dummy drug" without any active ingredients) and which …

40 - 75 years of age All Phase 1

A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

This study will be conducted to compare Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy.

2 - 17 years of age All Phase 2
T Taylor McKenzie

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases

The aim of the study is to generate patient-derived organoids (PDOs) from brain resection or biopsied extra-cranial metastases. The preliminary data collected will be used to assess the ability of PDOs to predict patients' treatment response and their radio-sensitivity and chemo-sensitivity can be correlated with their survival outcome.

18 years of age All Phase N/A
B Bhavna Ramchurn

Metagenomics for Ocular Inflammation

The aim of this study is to apply a diagnostic test called 'metagenomic sequencing' to identify the involvement of potential infections in patients with ocular inflammation, where this hasn't been detected by currently available standard testing. For many people with ocular inflammation, no cause is ever found for their disease. …

years of age All Phase N/A
K Karyn E Chappell, PhD

Magic Angle Direction Imaging (MADI) ACL Study

This study will be conducted to see if a new Magnetic Resonance Imaging (MRI) scanner could give additional information or help view the body in a different way. The new scanner may be useful to diagnose conditions affecting tissues such as ligaments, tendons and cartilage more accurately, potentially improving the …

18 - 65 years of age All Phase N/A

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