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Basildon, United Kingdom Clinical Trials

A listing of Basildon, United Kingdom clinical trials actively recruiting patients volunteers.

Found 26 clinical trials
M Mark C Petrie, MbChB

Use of a Novel SUBCUTaneous Preparation of Furosemide to Facilitate Early Supported Discharge of Patients With Heart Failure

To investigate whether an early supported discharge strategy for patients admitted to hospital because of HF, using a pH neutral subcutaneous (SC) furosemide formulation (SQINFurosemide) at home (delivered by non-CE marked SQINInfusor), compared to a usual care strategy with intravenous (IV) furosemide in hospital, results in an increased number of …

18 years of age All Phase 2
N Nick Curzen, BM (Hons) PhD FRCP

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina

ORBITA-MOON is a double-blinded, placebo-controlled experimental study that aims to understand how the different coronary artery stenoses contribute to overall clinical angina in patients with multi-vessel coronary artery disease. This study will investigate the symptoms conferred by each stenosis, induced by experimental ischaemia, for 60 patients with multi-vessel coronary artery …

18 years of age All Phase N/A
C Carol L Alves, BSc, MRes

REmotely Supervised Exercise Therapy Trial 2

Supervised exercise for intermittent claudication is a first line therapy for peripheral arterial disease, as recommended by the National Institute for Health and Clinical Excellence and the European Society for Vascular Surgery. However 2/3 of British trusts cannot implement this due to gym availability, costs, travel time and the requirement …

18 years of age All Phase N/A
K Kamalram Thippu Jayaprakash

Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma

Phase III randomised-controlled trial for patients with unilateral malignant pleural mesothelioma (MPM).

18 years of age All Phase N/A
T Thomas Keeble, MRCP PhD

The IMPACT PAD Study

Defining the role of intraprocedural physiology measurements in peripheral endovascular treatment

18 years of age All Phase N/A
L Louise Nimako

MIDI (MR Imaging Abnormality Deep Learning Identification)

The study involves the development and testing of an artificial intelligence (AI) tool that can identify abnormalities using patient head scans conducted for routine clinical care and research volunteer scans. A deep learning algorithm will be developed using a dataset of retrospective and prospective MRI head scans to train, validate, …

18 years of age All Phase N/A

Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)

A multi-centre observational study recruiting prospective and retrospective cohorts of patients with polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). The primary aim is to find genetic determinants of GCA and PMR susceptibility, in order to yield novel insights into disease pathogenesis. A subset of the retrospective cohort is also …

50 years of age All Phase N/A
N Neil Srinivasan, MBBS

Outcomes of Functional Substrate Mapping of Ventricular Tachycardia

The goal of this registry database is to demonstrate the safety and effectiveness of functional ventricular tachycardia (VT) ablation using SENSE protocol in patients with ischaemic VT. Mortality and the need for ICD therapies at 12 months post-ablation will be compared with propensity-matched controls undergoing substrate-based ablation alone.

18 years of age All Phase N/A
B Boston Scientific Clinical Research

RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine …

18 years of age All Phase N/A
T Tom Jackson

UK Heart Failure With Preserved Ejection Fraction

Heart failure occurs when the heart is no longer able to pump blood around the body properly. It can cause breathlessness, swollen feet and ankles, and tiredness. In about half of patients with heart failure, one measure of the heart's pumping function, called the 'ejection fraction', is normal. This type …

18 years of age All Phase N/A

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