Advanced Filters
noise

One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials

Pyrotinib Combined With Trastuzumab and Chemotherapy Neoadjuvant Therapy for HER2-positive Breast Cancer

This study is a prospective, single-center, observational clinical study, The objection was to observe the treatment of pyrotinib combined with trastuzumab and neoadjuvant chemotherapy Efficacy of Stage II-III breast cancer and observation of the efficacy of step-down neoadjuvant therapy for HER2-positive stage T1cN0M0 breast cancer.

18 - 75 years of age Female Phase N/A
B BoHeng Zhang, PHD

Enoxaparin for Preventing the Radical Artery Occlusion After the Transradial Access Hepatic Arterial Infusion Chemotherapy

The present investigation is designed as a single-blind, randomized, controlled, bicentric trial. The objective is to ascertain whether the subcutaneous administration of enoxaparin sodium for prophylactic anticoagulation during transradial hepatic arterial infusion chemotherapy (HAIC) can diminish the incidence of radial artery occlusion (RAO) post-procedure

18 - 69 years of age All Phase 2
J Juliane Calvez, PhD

Validation of the Dual-isotope Method for Measuring Ileal Protein Digestibility

The dual isotope method has been recently developed and used to evaluate indispensable amino acid (IAA) digestibility of various protein food such as legumes, eggs and chicken meat in healthy adults and children. The dual isotope method is an indirect method based on the measurement in plasma of absorbed IAA …

18 - 45 years of age All Phase N/A
T Travis Boulter

Low-dose Naltrexone for Post-COVID Fatigue Syndrome

This study aims to determine if low-dose naltrexone (LDN) reduces fatigue, improves related symptoms, and reduces inflammatory markers in peripheral blood in cases with Post-COVID-19 Fatigue Syndrome (PCFS) from COVID-19 (i.e. confirmed SARS-CoV-2 case). LDN refers to naltrexone given in doses of 1-4.5 mg. Overall, studies have found that LDN …

19 - 69 years of age All Phase 2
R Ruquan Han, M.D., Ph.D

Oxygen Concentration Target in Stroke Endovascular Treatment

The goal of this clinical trial is to compare the effects of different concentrations of normobaric oxygen on early neurological improvement in acute ischemic stroke (AIS) patients receiving endovascular therapy (EVT). The main questions it aims to answer are: Evaluating the impact of normobaric high-concentration oxygen versus low-concentration oxygen on …

18 years of age All Phase N/A
C Ceylan GÜZEL İNAL, Lecturer

The Effect of Two Non-pharmacological Methods on Pain and Anxiety Experienced During Intrauterine Device Application.

The purpose of this study is to determine the effect of emotional freedom technique and music, which are effective in relieving pain and anxiety, on the pain and anxiety that occur during intrauterine device application.

18 - 49 years of age Female Phase N/A
N National Cancer Institute Referral Office

Enasidenib in IDH2-Mutated Malignant Sinonasal and Skull Base Tumors

Background Cancers of the nasal cavity or skull base are rare. They often are not diagnosed until they are at an advanced stage, and they often spread to other parts of the body. These cancers may have mutations in a gene called IDH2. Researchers want to find out if a …

18 - 120 years of age All Phase 2
C Chaoying Hu

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

The objective of this clinical trial is to investigate the safety and tolerability of single ascending dose ACC017 tablets in Chinese healthy adult participants. This study aims to address the following major questions: Recommended dosage for ACC017 tablets used in phase Ib/IIa trial; The pharmacokinetic (PK) characteristics of single dose …

18 - 55 years of age All Phase 1
B Brandi Childers

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

The goal of this interventional study is to establish a whole food, avocado, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development. Eighty-eight breastfeeding dyads, 3m postnatal, will participate in this study designed to: To document whether lactating mothers will comply in …

18 - 40 years of age All Phase N/A

Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach

In France, more than 110.000 patients are hospitalized for stroke per year. It is the leading cause of sudden disabilities in adults. Incidence of spastic foot is evaluated at 1 year post stroke from 18% to 56% of hemiplegic patients. Spasticity, defined as an increase in the velocity-dependent response to …

18 - 100 years of age All Phase N/A

Simplify language using AI