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One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 64,772 clinical trials
C Casey L Straud, PsyD

Combining Esketamine and Prolonged Exposure Treatment for PTSD (Post Traumatic Stress Disorder)

This study is being done to see if Prolonged Exposure (PE), a well-researched, very effective individual (one-to-one) behavioral therapy designed to help people to directly deal with traumatic events they have suffered in the past, can be combined with intranasal esketamine (ketamine) for the treatment of posttraumatic stress disorder (PTSD) …

18 - 65 years of age All Phase 1/2
C Clinical Trial Referral Office

Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers

This phase II trial compares therapeutic plasma exchange followed by enfortumab vedotin and pembrolizumab to standard of care next-line therapy for the treatment of patients with bladder or upper urinary tract cancers that have spread from where they first started (primary site) to other places in the body (metastatic) and …

18 years of age All Phase 2

Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype

This trial studies a type of advanced breast cancer defined as hormone receptor HR-positive/HER2-negative and classified as non-luminal by gene expression profiling (PAM50). Patients will be treated with trastuzumab deruxtecan (T-DXd) or with physician's choice of CDK4/6 inhibitor (CDK4/6i) plus endocrine therapy (ET). The main purpose of the study is …

18 years of age All Phase 2
C Chris Lievens, OD

Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses

Determine the likelihood of successfully refitting a satisfied AOA CL wearers into P7A CLs

18 - 40 years of age All Phase N/A
K Kajsa Rosen, Physical Therapist (MAR)

ASSIST 2.0: a Reablement Program for Healthy Ageing

The goal of this study is to continue to develop, implement, and evaluate a unique reablement service, ASSIST 2.0. The project will determine the differences in the reablement service (ASSIST 2.0) compared to regular home care in terms of older adults' performance in daily activities, self-efficacy, perceived health, quality of …

65 years of age All Phase N/A
K KINZA ANWAR, MS-OMPT

Comparison of Sustained Natural Apophyseal Glide &Amp; Instrument Assisted Soft Tissue Mobilization

The aim of this randomized controlled trial is to evaluate and compare the effectiveness of two therapeutic techniques-Cervical Sustained Natural Apophyseal Glide (SNAG) and Instrument-Assisted Soft Tissue Mobilization (IASTM)-in the treatment of mechanical neck pain. The trial seeks to determine which method is more effective in reducing pain, improving range …

20 - 45 years of age All Phase N/A
L Lise Laclautre

Prevention of HEMOrhagic Risk in Upper MYOmeCTomy by Use of Misoprostol.

In France, uterine fibroids or leiomyomas are the most common benign tumour in women of childbearing age. In 30% of cases, fibroids are symptomatic (menorrhagia, anaemia, pain), in which case surgical management is indicated. This is known as myomectomy, and can be performed by hysteroscopy, laparoscopy (laparoscopy) or laparotomy, depending …

18 - 43 years of age Female Phase N/A
M Michael S Esterman, PhD

Suicide Risk Interventions

The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan. Accordingly, Veteran suicide prevention has been identified as a national healthcare and research priority. The investigators will recruit 136 female and male Veterans who have been hospitalized for …

18 years of age All Phase 2

Phase Ib/II Study of HRS2398 in Combination With Adebrelimab in Patients With Advanced Solid Tumors

This study is a multicenter, open-label, dose-finding/efficacy-expanding phase Ib/II clinical trial, which aims to observe and evaluate the tolerability, safety, pharmacokinetic characteristics and immunogenicity of HRS2398 combined with Adebrelimab injection in patients with advanced solid tumors, determine the RP2D, and preliminarily evaluate the efficacy of HRS2398 combined with Adebrelimab in …

18 - 75 years of age All Phase 1/2
J Jia Wei, PhD

Clinical Trial of CD123-targeted CAR-NK Therapy for Relapse/refractory AML or BPDCN

This is a clincal trial initiated by investigator to evaluate the safety and efficacy of anti-CD123 CAR-NK in the treatment of patients with relapsed/refractory acute myeloid leukemia or blastic plasma cell like dendritic cell tumors.

18 - 75 years of age All Phase 1

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