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One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 64,772 clinical trials
S Serena Barbaro, M.Sc.

Pembrolizumab in Locally Advanced Sinonasal Carcinoma

This study will test the Safety and activity of pembrolizumab plus chemotherapy as neoadjuvant treatment in locally advanced sinonasal undifferentiated carcinoma (SNUC). Activity of neoadjuvant chemotherapy in locally advanced SNUC has been already demonstrated; the primary hypothesis is that the addition of pembrolizumab as neoadjuvant and adjuvant agent might confirm …

18 years of age All Phase 2

Efficacy and Safety of GNT0003 Following Imlifidase Pre-treatment in Severe Crigler-Najjar Syndrome

Clinical trial rationale: CNS is an ultra-rare (<1/1 million newborns), autosomal recessive disorder of bilirubin conjugation caused by mutation in the gene coding for uridine 5'-diphosphate glucuronosyltransferase (UGT1A1), that causes the accumulation of neurotoxic unconjugated bilirubin (UCB). Reduction of UCB is managed with phenobarbital in mild CNS, and daily phototherapy …

18 years of age All Phase 2
A Ashley Servais

A Study of Venetoclax in Combination With Isatuximab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

A phase 2 study of venetoclax in combination with isatuximab and dexamethasone for relapsed/refractory multiple myeloma patients with t(11;14)

years of age All Phase 2
E Elise Nelson

Taltz in Combination With Enstilar for Psoriasis

Enstilar in combination with Taltz for plaque psoriasis.

18 years of age All Phase 4
M M. Los, dr.

Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5)

Since patients with borderline resectable pancreatic cancer (BRPC) have a limited life expectancy, it is important to improve treatment strategies. Therefore, the objective of this study is to investigate whether neoadjuvant triple treatment chemotherapy, immunotherapy and radiotherapy, followed by surgery and chemotherapy and immunotherapy survival in patients with BRPC.

18 years of age All Phase 1/2

A Study of LY4088044 in Healthy Participants

The purpose of this study is to evaluate how well LY4088044 is tolerated and what side effects may occur in healthy participants. The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to check …

18 - 65 years of age All Phase 1
J João R. Vaz, PhD

Neural Adaptations to Metronome-Paced Strength Training

The aim of the study is to investigate the effects of incorporating variability within Resistance Training (RT) methods on the neural adaptations along the corticospinal tract and on neuromuscular function. The literature suggests that RTis one of the most common modalities to enhance and restore muscle function and its practice …

18 - 40 years of age Male Phase N/A
Y Ying Wang, Doctor

Sintilimab in Combination with Cetuximab and Chemotherapy As First-line Treatment for RAS/BRAF Wild-type Advanced Colorectal Cancer

In 2018, global cancer incidence reached 18.1 million new cases, with 9.6 million cancer-related deaths. Colorectal cancer ranked as the third most common malignancy by incidence. Data from the U.S. NIH SEER database indicate a five-year survival rate for colorectal cancer of approximately 65%. Specifically, the survival rate is 90% …

18 - 75 years of age All Phase 1/2
N Nucleus Network Brisbane

A Study of CPTX2309 in Healthy Participants

The purpose of this study is to assess the safety and tolerability of CPTX2309 in healthy adult participants.

18 - 55 years of age All Phase 1
D Derek Nee, PhD

iTBS/fMRI Study of Apex Control

The objective of this study is to examine the effect of transcranial magnetic stimulation (TMS) on the prefrontal cortex and posterior parietal cortex.

18 - 30 years of age All Phase N/A

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