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One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials
J Jennifer Villers, PhD

In-depth Analysis of the Immune Responses in the Upper Respiratory Tract in Older Adults Infected or Colonized With Streptococcus Pneumoniae (Spn)

The NoseSpn-Elderly study aims at characterizing the immune response in the upper respiratory tract in adults aged 60 and over diagnosed with a pneumonia due to a Streptococcus pneumoniae (Spn) infection. The immune response during the acute phase of the infection and after recovery will be compared to the immune …

60 - 85 years of age All Phase N/A
D Dominique Bertrand, MD

Alloreactive Memory B Lymphocytes and Anti-HLA Sensitization

In transplantation, B lymphocytes are major cellular players in the alloreactive humoral response through the production of antibodies targeting allogeneic HLA molecules expressed by the transplant. In subjects sensitized to HLA antigens, the contribution of pre-existing alloreactive memory B lymphocytes (Bmem) to allograft rejection phenomena after transplantation is now recognized. …

18 years of age All Phase N/A
M Marco Della Sanità, RN

Readmission and Dehydration Prevention in Patients With Elective Ileostomy

The goal of this prospective observational study is to evaluate the adherence to DRIP score calculation and the application rate of each proposed item to prevent dehydration and readmission in patients undergoing ileostomy creation after elective colorectal resection different Italian colorectal surgical centers. The primary endpoint is to verifythe application …

18 years of age All Phase N/A

FAPI Imaging Predicts Adverse Cardiac Events in Chronic Total Occlusion

Prospective, observational, single-center cohort study Hypothesis Higher myocardial FAPI uptake in CTO patients predicts a greater incidence of major adverse cardiovascular events (MACE) within 12 months after PCI. FAPI PET/CT imaging is associated with plaque vulnerability features and may serve as a non-invasive marker for fibrotic activity and adverse cardiac …

18 years of age All Phase N/A
D Dhandayuthapani Rajkumar

Experiences of Managing Sleep Disordered Breathing in Children With Cerebral Palsy.

Cerebral palsy (CP) refers to a non-progressive movement disorder, which occurs due to damage to the developing brain around the time of birth. Symptoms of sleep disordered breathing (SDB) include noisy breathing during sleep, increased day-time sleepiness and reduced energy levels. In the long term, SDB might have an effect …

1 - 16 years of age All Phase N/A
R Raphaël PIETTON, MD

Prevalence of Diabetes in Patients Who Are Candidates for Spine Surgery

The purpose of the study is to assess, through systematic screening, the prevalence of diabetes or prediabetes in patients who are candidates for lumbar spine surgery.

18 years of age All Phase N/A
E Eduard Charchyan, professor

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle …

18 years of age All Phase N/A

Bolt CSP-M Holter Study

The purpose of this study is to investigate the cardiac electrical characteristics in different pacing outputs and body positions in LBB area pacing (LBBAP), from which the findings may help to develop and support data validation of a novel algorithm for LBB capture determination for LBBAP.

18 years of age All Phase N/A

Rarecells Molecular Biomarkers for Early Detection of Lung Cancer

Early diagnosis of lung cancer is a public health priority. Additionally, early detection of recurrences after treatment is crucial for optimizing disease management. This study seeks to demonstrate the accuracy of the Rarecells ISET® circulating tumor cells DNA (CTC-DNA), combined with circulating tumor DNA (ctDNA), for the early diagnosis of …

35 - 85 years of age All Phase N/A
A Areen Khoury, DMD

Nerve Block Treatment for Chronic Jaw Pain

Study Summary: Nerve Block Treatment for Chronic Jaw Pain This study is being conducted at the TMJ (temporomandibular joint) clinic, which is part of the oral and maxillofacial surgery department. The goal is to evaluate how effective peripheral nerve blocks are in reducing long-term jaw pain in patients with chronic …

18 years of age All Phase N/A

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