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One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 64,783 clinical trials
J Johannes Koren, MD PhD

Multimodal Neuromonitoring

Theoretical Framework & Background Cortical spreading depressions (CSD) and seizures, are crucial in the development of delayed cerebral ischemia and poor functional outcome in patients suffering from acute brain injuries such as subarachnoid hemorrhage. Multimodal neuromonitoring (MMNM) provides the unique possibility in the sedated and mechanically ventilated patients to record …

18 - 80 years of age All Phase N/A
K Karol RawiczPruszyński, Professor

MalnutritiOn Assessment With biOelectrical impedaNce Analysis in gastRic Cancer patIentS Undergoing Multimodal trEatment

The aim of this single-arm prospective, multicenter, cross-sectional study is to evaluate the nutritional status and body composition on tumor regression grade with bioelectrical impedance analysis in gastric cancer patients undergoing multimodal treatment. Results of this study will reveal whether nutritional status and body composition assessment based on bioelectrical impedance …

18 - 100 years of age All Phase N/A
O Olga Plattner, MD

Gender-specific Preoperative Anxiety Level and Postoperative Opioid Requirement After ENT Surgery.

The study will be designed to investigate the impact of the preoperative anxiety level on postoperative opioid requirement during the PACU stay, in order to improve postoperative pain treatment in the long term after ENT surgery. The present study can contribute to improve postoperative pain management in patients in the …

18 years of age All Phase N/A
W Wei Lyu, MD

Gut and Vaginal Microbiota Profile Study for HIV Women

Women Living with HIV Infection (WLHIV)are intended to acquire HPV infection which usually contributes to variable cervical lesions. we hypothesize that vaginal microbiota imbalance may make WLHIV prone to HPV infection,thereafter results in severe cervical lesion.

14 years of age Female Phase N/A
N Natacha ENTZ WERLE

Cell Phone Application to Help Adolescents and Young Adults in Their Therapeutic and Educational Journey

About 2000 cancers/year in France are diagnosed in Adolescents and Young Adults (15-25 years old, AYA). The cancer plans and the INCA recommend support during and after cancer, taking into account both medical and psychosocial specificities related to age (supportive care, school learning/training and professional integration, fertility preservation, therapeutic education, …

15 - 25 years of age All Phase N/A
F Frédéric VALLA

Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children

Nearly half of critically ill children are intubated and enterally fed according to recent guidelines. However, no evidence-based recommendation are available regarding fasting times prior to extubation. When an extubation is planned, children do not always present with normal neurological status yet, and are at risk of vomiting and aspiration. …

- 17 years of age All Phase N/A
J Julio Cesar Palacio Villegas, Dr.

Clinical and Functional Outcome of the GEMINI SL Fixed Bearing PS Knee Prosthesis

This is a prospective, multicenter, observational study with a planned follow-up period of 10 years to confirm the safety and performance of the GEMINI SL Fixed Bearing PS knee prosthesis in longterm follow-up under routine conditions. Primary outcome of the study is the 10-year survival rate of the GEMINI SL …

18 - 80 years of age All Phase N/A

Bowel Cleansing With Renal Impairment

Bowel preparation for colonoscopy requires the administration of large amounts of fluids that can cause fluid and electrolyte disturbances and volume overload, especially in patients with advanced renal failure. Polyethylene glycol-based regimens are considered safe, even in patients with advanced renal failure. However, the incidence of adverse effects (AEs) in …

18 - 80 years of age All Phase N/A
A Anissa Megzari

Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients With Versus Without Intestinal Polyps

The study authors hypothesize that in patients with intestinal polyps, tumor cells could disseminate and circulating factors could be secreted by the polyp. These two parameters could become biomarkers to refine the follow-up of patients and to establish targeted therapeutic strategies.

18 years of age All Phase N/A
A Alessandro Belletti, MD

Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS)

Barotrauma (pneumothorax, pneumomediastinum) is a well-described complication of Acute Respiratory Distress Syndrome (ARDS), especially in patients with coronavirus disease 2019 (COVID-19) (16.1% in COVID-19, and about 6% in non-COVID-19 ARDS). Macklin effect was recently discovered by our group as an accurate radiological predictor of barotrauma in COVID-19 ARDS; the Investigators …

18 years of age All Phase N/A

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