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One or multiple investigational sites, Spain Clinical Trials

A listing of One or multiple investigational sites, Spain clinical trials actively recruiting patients volunteers.

Found 64,778 clinical trials
Y Yang Xiang

Toripalimab Plus Actinomycin-D As Fist-Line Treatment for GTN with FIGO Score 7

The goal of this clinical trial is to evaluate the efficacy and safety of toripalimab plus actinomycin-D as fist-line treatment in patients with gestational trophoblastic neoplasia with FIGO score 7. The main questions it aims to answer are: Whether toripalimab plus actinomycin-D as fist-line treatment can achieve a high complete …

18 - 60 years of age Female Phase 2
M MAROULLA I NIKOLAKI, phD (c)

Digestive Enzyme Formulation Intervention in IBS Patients Who Previously Clinically Responded to Mediterranean LFD

Irritable bowel syndrome (IBS) is a highly prevalent chronic functional gastrointestinal disorder. The cardinal symptoms include abdominal pain, flatulence, bloating, and changes in bowel habits related to stool frequency and consistency, in the absence of detectable structural and biochemical abnormalities1,2. The prevalence is estimated at 5-10% among different ethnicities3. A …

18 - 65 years of age All Phase N/A
C Christian Carrwik, MD, PhD

Fusion or Not- a Randomized Controlled Study on Low Back Pain

Problems from the musculoskeletal system are one of the most common reasons for disability and sick leave. These problems include low back pain. Low back pain affects as many as 8 out of 10 individuals at some point in life. In most people it is quickly transient with little, or …

25 - 65 years of age All Phase N/A
B Babak Tofighi, MSc, MD

Using AI and Peer Coaching to Address Racial Disparities Among People Who Use Opioids

Black and Latinx people who use opioids are disproportionately impacted by opioid overdose deaths. The proposed study assesses the efficacy of an open source, multimodal artificial intelligence-driven texting tool combined with peer recovery coach-supported text contact that delivers social services, stigma reduction, health habitus, and patient navigation content addressing social …

18 - 99 years of age All Phase N/A
L Liu

Fenofibrate in Primary Biliary Cholangitis: a Real World Study

An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Fenofibrate in Combination with Ursodeoxycholic Acid in Subjects with Primary Biliary Cholangitis (PBC)

18 - 75 years of age All Phase 3
A Alexander Schwärzler DMD Prinzipal Investigator, DMD

Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.

Hard tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Soft tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Participants will undergo orthodontic treatment, including: Initial records (intraoral scan, CBCT (cone-beam computed tomography) scan, face scan) Placement of guided …

12 - 26 years of age All Phase N/A
N Nevin GÜZEL, Prof

Inspiratory and Expiratory Muscle Training in Adolescent Volleyball Players

This study will investigate the effects of inspiratory and expiratory muscle training on respiratory muscle strength, pulmonary function, and performance status in adolescent athletes

12 - 18 years of age Female Phase N/A
T Tianshu Liu

A Study of IMM2510 + IMM27M Combination Therapy in Patients With Advanced Solid Tumors

This study is an open-label, multi-centre, single-arm, phase I clinical study, to evaluate the safety, tolerability, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of IMM2510 (an anti-PD-L1/VEGF bispecific antibody fusion protein) + IMM27M (a humanized Fc-engineered anti-CTLA-4 antibody) combination therapy in patients with advanced solid tumors.

18 - 75 years of age All Phase 1
b bouchra benkessou, chef de projet

Study of Transaxillary Robotic Thyroidectomy Versus Standard Open Thyroidectomy: Prospective, Comparative Single-Center Study

The aim of our study is to evaluate the two surgical approaches, standard thyroidectomy and robotic thyroidectomy, in terms of postoperative pain management, scar quality, quality of life, as well as the occurrence of postoperative complications (hypocalcemia, compressive cervical hematoma and nerve stimulation)

18 years of age All Phase N/A
J Jeanne Zheng

CogniFit Computerized Cognitive Training in Primary School Students in Hong Kong

This study aims to address these gaps by conducting a comprehensive evaluation of the effects of CogniFit training in children. The primary objective of this study is to evaluate the effectiveness of CogniFit training on executive functions among primary school students in Hong Kong. Specific objectives include: To assess the …

6 - 12 years of age All Phase N/A

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