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Moscovskaya Oblast, Russian Federation Clinical Trials

A listing of Moscovskaya Oblast, Russian Federation clinical trials actively recruiting patients volunteers.

Found 152 clinical trials
B Bulat Bakhirov

Study of the Safety, Pharmacodynamics and Efficacy of ANB-002 in Patients With Hemophilia B (SAFRAN)

The goal of this multicenter, two-stage, open-label study is to investigate the safety, immunogenicity, and efficacy of ANB-002 in subjects with hemophilia В. The study will have a dose-escalation design with elements of phase I/II seamless adaptive design.

18 - 100 years of age Male Phase 1/2
T Taras Nechay, PhD

Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction

This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.

17 - 80 years of age Both Phase N/A
A Alexandra Ershova, MD, PhD

Genetic Testing and Motivational Counseling for FH

To date, there are highly effective lipid-lowering drugs, the combination of which makes it possible to achieve the target level of LDL-C in most patients with familial hypercholesterolemia (FH). However, the effectiveness of treatment of FH patients strongly depends on adherence to lipid-lowering therapy and to the healthy lifestyle, as …

18 - 100 years of age Both Phase N/A
M Mikhail M. Kostik

Efficacy and Safety of RPH-104 for Resolution and Prevention of Recurring Attacks in Adult Subjects With Familial Mediterranean Fever With Resistance to or Intolerance of Colchicine

The primary purpose of this study is to assess the efficacy and safety profiles of investigational product RPH-104 (R-Pharm Overseas, Inc., USA) for treatment of Familial Mediterranean Fever (FMF) in adult patients resistant/intolerant to colchicine (crFMF). Pharmacokinetic and pharmacodynamic parameters of RPH-104 single or multiple doses in this patient population …

18 - 100 years of age Both Phase 2

GNR-084 Safety and Pharmacological Characteristics in Refractory or Relapse B-cell Precursor ALL

It is an open-label dose-escalating study in sequential cohorts to assess safety and pharmacokinetics of GNR-084.

18 - 45 years of age Both Phase 1/2
G George Plotnikov, PhD

A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction

There are 10.3 million cases of stroke registered in the world every year; 63% of them lead to death. According to World Health Organization, stroke is one of the most important risk factors of death and early disability. Carotid artery surgery is a gold standard of hemodynamically significant carotid artery …

18 - 100 years of age Both Phase 3
S Sergey S Gordeyev, PhD

Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection

The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair. The main question it aims to answer is: can mesh help prevent hernia? Participants will be divided into 2 groups: with …

18 - 85 years of age Both Phase 3

Evaluation of the Effectiveness of Extracorporeal Methods for Removing Mediators of Systemic Inflammation

The purpose of this study is to assess the effectiveness and the safety of extracorporeal methods for removing mediators of systemic inflammation in patients with multiple organ dysfunction syndrome after heart and aorta surgery.

18 - 100 years of age Both Phase N/A
M Marina Biryukova, MD

Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse

This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse

18 - 70 years of age Female Phase 3
M Mariia V Smagina

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A

The goal of this multicenter, two-stage, open-label study is to investigate the safety, immunogenicity, and efficacy of ANB-010 in subjects with hemophilia A. The study will have a dose-escalation design with elements of phase I/II seamless adaptive design.

18 - 100 years of age Male Phase 1/2

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