A, Almada N Clinical Trials

V Vibeke Brix Christensen, MD, PhD, DMSc

BILACO Trial: Biliary Atresia - a Severe Complex Congenital Liver Disease

Biliary atresia is the most severe form of cholestatic liver disease. The children have high morbidity and mortality and get devastating pruritus and fatigue, failure to thrive, progressive hepatic failure and impaired neurodevelopment. The etiology is mostly unknown. More than half need a new liver from a living or deceased …

M Moshe Frenkel, MD

Feasibility of Integrating Homeopathic Approach in a Comprehensive Cancer Center

Supportive and palliative care play an important role in cancer treatment, and when introduced early can improve quality of life and may even increase median survival rates, as shown in patients with advanced lung cancer. Complementary and integrative medicine (CIM) is a popular supportive approach among oncology patients and is …

J Jean Baptiste FASSIER, MD

Realistic Evaluation of a Job Retention Program After Breast Cancer

Returning to and maintaining employment after cancer is essential for restoring social participation, financial independence and reducing the social costs associated with cancer. Many obstacles that prevent or delay the return to work have been identified. They are associated with the consequences of the disease and treatments such as fatigue, …

Y Yongchang Zhang, MD

A Non-interventional Study With Advanced Lung Squamous Cell Carcinoma

This is a descriptive observational study, in which data are collected in an epidemiological fashion and prospective. This study does not intend to intervene the current medical practice of the recruited patients.

OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry.

The OSPREY Patient Registry has been developed to collect and assess the performance and safety of the OncoSil™ device when used within the approved indication of unresectable, locally advanced pancreatic cancer, in combination with gemcitabine-based chemotherapy, within a real-world observational registry. The Registry data will provide both complementary and contemporary …

B Ben Chew, MD

Development of a New Canadian Endourology Group Stent Symptom Score

Placement of a ureteral stent is a common urological intervention. For decades there was no valid measures available to assess quality of life issues in patients with ureteral stents, which has hampered the understanding of such symptoms and their true impact. In order to improve the outcomes associated with the …

Y Yin-Hsiu Chien, MD, PhD

A Long-term Study for the Outcome of Pompe Disease

Prospectively follow patients with Pompe disease underwent enzyme replacement therapy.

J Julie Steen

A Novel Study Evaluating Patients Awaiting Total Hip Arthroplasty (PRIORITEES)

Hip replacements are one of the NHS's highest volume procedures, with ~14,000 operations per month before the onset of the COVID-19 pandemic. Delays to surgery can have significant implications; meaning increasing levels of pain and worsening quality of life. As of January 2021, following the initial waves of the COVID-19 …

R Rena Buckstein, MD

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications

'CHIP' stands for Clonal Hematopoiesis of Indeterminate Significance, which are mutations in bone marrow stem cells that give that population of cells a survival or 'clonal' advantage for growth. This study investigates whether CHIP in lymphoma patients aged 60 years and older is a risk factor for chemotherapy-related complications like …

J Josee-Lyne Ethier, MD, M.Sc.

Using a Blood Test to Monitor Metastatic Breast Cancer Treatment

The goal of this observational study is to assess the effectiveness of the mDETECT breast cancer blood test at monitoring treatment response in women with metastatic breast cancer undergoing treatment.