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A, Almada N Clinical Trials

A listing of A, Almada N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials
K Kar Yee Lor, MBChB

A Comparison of THD® Anopress With High Resolution Anorectal Manometry

Currently, high resolution anorectal manometry (HDARM) is used as gold standard to measure anal sphincter pressures in women who have sustained a third or fourth degree perineal tears (obstetric anal sphincter injuries). This test is performed to help advise patients on future pregnancies or deliveries. However, HDRM catheters are very …

18 years of age Female Phase N/A

A Phase I Study of LX22001 for Injection in Healthy Subjects

Study to evaluate the safety and tolerability, pharmacokinetics/pharmacodynamics (PK/PD) parameters of an escalating, single dose/repeat doses of LX22001 for injection in healthy subjects.

18 - 45 years of age All Phase 1
L Lynne Bell

Investigating the Effects of a Haskap Berry Supplement on Cognitive Health

This study aims to investigate the postprandial (2h) and longer term (4 week) effects of a haskap berry supplement on cognitive, vascular, and metabolic function in healthy ageing adults aged 50+.

50 years of age All Phase N/A
J Jaya (Mini) Gill

A Study to Examine Anktiva for the Treatment of COVID-19.

This study will examine the safety and effectiveness of Anktiva in treating patients with Long COVID-19 which is defined as persistent symptoms of a COVID-19 infection that remain after the infection is over.

18 - 70 years of age All Phase 2
W Weijing Zhang

A Study of HS-20124 in Patients with Advanced Solid Tumors

HS-20124 is a novel DAR-8 antibody-drug conjugate (ADC) targeting CDH6. In preclinical studies, it inhibited tumor cell growth expressing CDH6 in vitro and in vivo. The first-in-human trial is conducted to assess the maximum tolerated dose (MTD) and dose limiting toxicity (DLT), to evaluate the pharmacokinetics, safety and preliminary anti-tumor …

18 years of age All Phase 1
D Dezhi Clinical Operation derictor

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

This study is a multicenter, open-label, phase I/II study of YL205 in China to evaluate the safety, tolerability, PK characteristics and preliminary efficacy of YL205 in the following selected patients with advanced solid tumors.

18 years of age All Phase 1/2
J Jette Lautrup Frederiksen, Prof, MD

Indole-3-PROpionic Acid Clinical Trials - a Pilot Study Part 2

The goal of this trial is to investigate the biological effects of oral supplementation with indole-3-propionic acid (IPA) taken twice daily in healthy adults. The main scientific questions are: Does supplementation with IPA increase the abundance of regulatory T cells in the blood? Regulatory T cells are believed to play …

18 - 65 years of age All Phase N/A
J Jihui Hao, MD

A Clinical Study of CHT102 in Mesothelin Positive Advanced Solid Tumors

Objectives of Study:In this study investigators plan to evaluate the safety and efficacy of MSLN-targeting Universal Chimeric Antigen Receptor T-Cell Immunotherapy(U CAR-T) in the treatment of MSLN-positive advanced solid tumors.

18 years of age All Phase N/A
c carlalberta verna

The Use of a Pacifier to Correct Malocclusions in Young Children

The aim of the study is to investigate the effect of a pacifier (102 Medical Pacifier, Curaprox, Switzerland) on malocclusions like posterior crossbite, anterior open bite, larger overjet and tongue dysfunction in young children.

2 - 5 years of age All Phase N/A
M Michelle Wine Chief Psychologist, Ph.D.

Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors

The primary aim of the project is to test the efficacy of BCBT delivered via a digital platform (i.e., smartphone) to Servicemembers with recent suicidal ideation and/or suicide attempts presenting to primary care clinics. Given existing challenges of scaling empirically-supported treatments/interventions for suicidality with fidelity, this project could lead to …

18 years of age All Phase N/A

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