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Krakow Poland, Poland Clinical Trials

A listing of Krakow Poland, Poland clinical trials actively recruiting patients volunteers.

Found 178 clinical trials
T Tomasz Skladzien, phd md

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Due to the increasing number of reports of cancer progression in people undergoing surgery under general anesthesia using opioids, OFA is believed to have a favorable long-term prognostic effect, especially in cancer patients. The opioid-free protocol is also used in postoperative analgesia. It is estimated that up to 75% of …

18 - 80 years of age All Phase N/A
K Krzysztof Klos, Lieutenant Colonel, MD, PhD

Comparison of Three Interventions for Antibiotic-Resistant Bacteria (ARB) Decolonization From the Gastrointestinal Tract

The aim of this research experiment is to evaluate the effectiveness of fecal microbiota transplantation (FMT) preceded by antibiotic pre-treatment versus probiotic therapy and a standard-of-care equivalent diet designed to stimulate the growth of eubiotic gut microbiota (an active comparator enhancing the ethical value of the study and increasing the …

18 years of age All Phase N/A

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)

The purpose of this study is to assess the safety and efficacy of NT 201 compared with placebo in participants with moderate to severe platysma prominence. The study will be conducted in two periods: Main Period (MP) and Open label Extension Period (OLEX).

18 - 65 years of age All Phase 3
P Piotr Fudalej

Impacted Canine and Mixed-reality Technology - RCT

The goal of this clinical trial is to determine whether the use of HoloLens 2 mixed reality goggles for planning alignment of palatally impacted canine reduces: 1) treatment time and 2) the risk of complications compared to planning alignment of palatally impacted canine without HoloLens 2 goggles. Participants will have …

10 - 20 years of age All Phase N/A

RVU120 in Patients With Intermediate or High-risk, Primary or Secondary Myelofibrosis

The objective of this clinical trial is to evaluate the efficacy (how well the drug works), safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the study drug, RVU120, in treating adult patients with intermediate or high-risk, primary or secondary myelofibrosis. RVU120 will be given as a single agent or in combination …

18 years of age All Phase 2
G Grzegorz Helbig, Prof. dr hab. n. med

Obinutuzumab Versus Rituximab for Acute Lymphoblastic Leukemia/PALG ALL7 "OVERALL"

A multicenter, prospective, randomized and controlled study to compare the efficacy and safety of obinutuzumab and rituximab in adult ALL patients with CD20 expression.Study population is 124 patients (62 in each study group).

18 years of age All Phase 2

MEN1703 (SEL24) to Treat Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma (JASPIS-01)

The goal of the study is to assess the safety and anti-lymphoma activity of MEN1703 (Dapolsertib hydrochloride) when given as a single-agent or combined with glofitamab to patients with relapsed/refractory (R/R) aggressive B-cell non-Hodgkin lymphoma. The study will be open to groups at the same time: Group 1 - patients …

18 years of age All Phase 2
E Edyta Laska, Ph.

Assessment of Quality of Life and Independence, as Well as Received Social Support for Spinal Cancer.

Evaluation of the quality of life of patients before and after surgery for benign and malignant spinal cancers, assessing whether it depends on the size of the tumor, type of cancer, malignancy and its location evaluation of patients' independence before and after surgery for benign and malignant spinal tumors, evaluation …

years of age All Phase N/A
J Julian Dutka, Professor of medical sciencess

Psychological Factors and Pain in Orthopedic Surgery Patients

The goal of this observational study is to verify the association of previously underexplored psychological variables on postoperative pain experience and its progression over time in patients undergoing emergency and elective orthopedic surgeries, including both sexes (age range: 18-65). The main questions it aims to answer are: Do psychological factors …

18 - 65 years of age All Phase N/A

Ravulizumab Treatment Outcomes in Patients With Generalized Myasthenia Gravis

The Polish multicentre observational (non-interventional) study aiming to collect data on the management and clinical outcomes of patients with gMG that received ravulizumab.

18 years of age All Phase N/A

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