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Meppel, Netherlands Clinical Trials

A listing of Meppel, Netherlands clinical trials actively recruiting patients volunteers.

Found 79 clinical trials

High-Risk prostatE Cancer radiatiOn Versus surgERy

Prospective cohort study comparing robot-assisted radical prostatectomy and external beam radiotherapy combined with androgen deprivation therapy for high-risk non-metastatic prostate cancer in terms of health-related quality of life, functional outcomes, cost-effectiveness, progression-free survival and distant metastasis-free survival.

50 - 75 years of age Male Phase N/A
M M. Koopman, dr.

Prospective Data Collection Initiative on Colorectal Cancer

Survival after colorectal cancer (CRC) diagnosis strongly depends on local tumor extent, lymph node involvement and the presence of distant metastases. However, there remains great inter-patient variability regarding treatment outcome. A combination of biochemical factors, histopathological features, genomic profile, environmental factors and other clinical factors are likely to influence prognosis …

18 - 100 years of age Both Phase N/A
A Arno M Wiersema, MD, PhD

Measuring the ACT During Non-cardiac Arterial Procedures.

Aim of the MANCO study is to establish for once and for all that monitoring the effect of heparin during NCVI (Non-Cardiac Vascular Interventions) is essential to ensure the individual patient of safe and tailor-made anticoagulation. Not measuring the effect of the administered heparin exposes the patient to unnecessary risks …

18 - 100 years of age Both Phase N/A
A Aline H Vrieling

Effectiveness and Cost-effectiveness of Lower Limb Prostheses

The goal of this observational study is to investigate the effectiveness of NMPKs versus MPKs in persons with an LLA in the standard healthcare system in the Netherlands taking all levels of the ICF model into account. Our main aim is to assess the effect of MPK use compared to …

18 - 100 years of age Both Phase N/A
C Caroline Muntinga, MD

Predicting Response In Cervical Intraepithelial Neoplasia to Topical Imiquimod Treatment

Imiquimod is a good non-invasive treatment option for women with cervical high-grade squamous intraepithelial neoplasia (cHSIL), especially those with a possible (future) pregnancy wish. Complete response to imiquimod occurs in 55-73% of patients, however side-effects of imiquimod are common and can be extensive. Therefore, biomarkers which can predict response to …

18 - 100 years of age Female Phase N/A
D D. J. de Groot, MD, PhD

Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer

In this study the characteristics and alterations of the gut microbiome during chemotherapy for metastasized or irresectable CRC are studied, as well as the relation between the gut microbiome and the effects of chemotherapy.

18 - 100 years of age Both Phase N/A
W Wytze de Boer, MD

Sonographic Diaphragm Function in AECOPD

The study will be conducted as a single-center, prospective cohort study. The primary objective of this study is to investigate the responsiveness of sonographic parameters of diaphragm to detect change in Borg score for dyspnea during hospitalisation for AECOPD without respiratory acidosis.

18 - 100 years of age Both Phase N/A
M Marit van der Sande, MD

"Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer

The aim of this prospective observational cohort study is to provide short and long term oncological and functional outcome data on organ preserving treatment in good responders after a standard indication for neoadjuvant (chemo)radiation for rectal cancer.

18 - 100 years of age Both Phase N/A
E Elise Doppenberg-Smit, Msc

Adaptive and Maladaptive Emotions in Patients With Cancer: Identification of Indicators

Primary Objective: To identify indicators distinguishing between adaptive and maladaptive emotions in patients with cancer.

18 - 100 years of age Both Phase N/A

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