Advanced Filters
noise

Enschede, Netherlands Clinical Trials

A listing of Enschede, Netherlands clinical trials actively recruiting patients volunteers.

Found 48 clinical trials
V Vera Hengeveld, MD

The Rainbow Study - the Effect of Feedback on Asthmatic Symptom Perception

Asthma is a common childhood disease that is characterized by chronic airway inflammation and episodic expiratory airflow obstruction. Asthma symptoms can impair participation in play and sports and have a negative impact on quality of life. It can be challenging for children to adequately feel and report their symptoms. Some …

7 - 15 years of age All Phase N/A
K Katarina Urbanova, Dr. rer. nat

EFFICACY of INTRAOPERATIVE ARISTA POLYSACCHARIDE APPLICATION on the POSTOPERATIVE BLOOD LOSS in PATIENTS UNDERGOING RARP for the TREATMENT of PROSTATE CANCER

Background and aim of the study: Radical prostatectomy (RP) is one of the most commonly used treatment options for localized prostate cancer (PCa). Blood loss and deterioration of erectile function is, however, a common unwanted side effect of RP. Previous series demonstrated that the robot-assisted RP (RARP) approach is associated …

45 - 68 years of age Male Phase N/A

Enhancing Successful Return to Work of Employees With Cancer, by Supporting Employers (MiLES Intervention)

The objective of this randomized controlled trial (RCT) is to evaluate the effectiveness of the MiLES intervention targeted at employers, on successful return to work (RTW) of employees with cancer, compared to care as usual (CAU). Secundary objectives are: To evaluate the cost-effectiveness and return-on-investment of the MiLES intervention on …

18 - 65 years of age All Phase 2/3
J Job van der Palen, Full professor

Cohort Multiple Randomized Controlled Trial in Pediatric Asthma

The overarching goal of this study is to optimize pediatric asthma care and to continuously evaluate variations/innovations of the care (including transformation to remote eHealth care). Primary Objectives within cmRCT cohort: Provide a framework for multiple randomized (eHealth) interventions for asthmatic children Generate short- and long-term data on Quality of …

4 - 18 years of age All Phase N/A
J Jette E. Van Egmond, drs.

Power2Walk: the Impact of Functional Power Training on Participation and Activity in Children with Cerebral Palsy.

Rationale: Children with cerebral palsy (CP) experience limitations in walking ability due to functional motor impairments caused by neurodevelopmental damage during fetal or early child development. Due to these motor impairments, children with CP struggle to keep up with typically developing peers when participating in physical and/or social activities. Consequently, …

4 - 12 years of age All Phase N/A
D Dr. L.J.C. van Warmerdam

Apa/Enza-short Study: Shorter Treatment With Androgen Receptor Pathway Inhibitor in Patients With Low-volume Metastatic Castration-sensitive Prostate Cancer

The goal of this clinical trial is to evaluate the outcomes of a shorter treatment duration (12 months) with an androgen receptor pathway inhibitor (ARPI), in this study Apalutamide or Enzalutamide, in patients with low-volume, hormone-sensitive metastatic prostate cancer (mCSPC), with the possibility to restart treatment if needed. The main …

18 years of age Male Phase 3

Coeliac Artery Release or Sham Operation

In patients with Median Arcuate Ligament Syndrome (MALS), significant external compression of the coeliac artery (CA) by the median arcuate ligament (MAL) increasing mucosal ischemia (1,2) is assumed to cause chronic disabling postprandial abdominal pain, weight loss, and consequently lethargy and social deprivation (3,8). The majority of these patients have …

18 years of age All Phase N/A

Lomustine With and Without Reirradiation for First Progression of Glioblastoma: a Randomized Phase III Study

Despite comprehensive multimodal treatment of newly diagnosed glioblastoma, almost all patients suffer from tumour relapse. Currently, no standard of care exists to treat these tumour relapses. Treatment options include repeated surgery (if feasible), systemic therapy (bevacizumab, lomustine, temozolomide re-challenge), reirradiation and best supportive care. Currently, the superiority of combined chemoradiation …

18 years of age All Phase 3
C Christian Thomas, Prof.

Virtual Interactive 3D Modelling to Improve Outcomes in Robotic-Assisted Partial Nephrectomy

The primary objective is to determine if 3D modelling shortens total console operation time as a surrogate endpoint for clinical outcomes like perioperative complications and morbidity in robotic-assisted partial nephrectomy.

18 years of age All Phase N/A

The Effectiveness of CFT for Reducing Self-criticism in Patients With Complex PTSD: a Single-case Experimental Study

PTSD is a mental disorder including psychological symptoms related to severe traumatic event(s). PTSD can negatively affect people's functioning in several life domains. Several effective therapies for the treatment of PTSD have been developed in recent decades. However, these treatments are not effective for every patient. Several studies show that …

18 - 65 years of age All Phase N/A

Simplify language using AI