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Tokyo and Other Japanese City, Japan Clinical Trials

A listing of Tokyo and Other Japanese City, Japan clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials
G Gary Bucher, MD

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants

This is a phase II double blind, placebo-controlled, randomized study of artesunate ointment for the treatment of HIV-negative men and women who have anal high grade squamous intraepithelial lesions (anal HSIL)

18 years of age All Phase 2
S SARTELET Lydie

Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects

stress. Notably, several studies reported that stress could alter impulsivity, source monitoring, and time perception. Several mechanisms are involved in the response to a stress factor, among them the hypothalamic-pituitary-adrenal (HPA) axis. The cortisol reactivity (it means the cortisol secretion after the exposure to a standardized stress factor) is a …

18 - 45 years of age All Phase N/A
E Eduardo Pirotzky, Doctor

Safety and Pharmacokinetics of IMT504, an Immunomodulator and Tissue Repair Inducer

Phase 1 open-label dose-escalation study to evaluate the safety and pharmacokinetics of IMT504 Phosphorothioate Oligonucleotide, an immunomodulator and tissue repair inducer, in healthy volunteers.

18 years of age All Phase 1
R Reham M Rezk, MBBCH

Ultrasound Guided Recruitment Manauvere Versus Individualized Positive End Expiratory Pressure in Pediatric Patients Undergoing Laparoscopic Abdominal Surgery

The aim of this prospective randomized controlled study is to compare the effect of US-guided Recruitment Manauvere (RM) versus individualized positive end-expiratory pressure (PEEP) on oxygenation and preventing respiratory complications in pediatric patients undergoing laparoscopic abdominal surgeries.

3 - 8 years of age All Phase N/A
E Eduardo Montero, MSc

Effect on Periodontal Phenotype of Flapless Piezoincission During Orthodontic Treatment

Research Question While the reduction in treatment times and the patient satisfaction after periodontally accelerated osteogenic orthodontics (PAOO) are well sustained in the scientific literature (Charavet et al., 2016; Charavet, Lecloux, Jackers, Maes, & Lambert, 2019), there is still controversy regarding if grafting leads to i) change of the periodontal …

16 - 70 years of age All Phase N/A
M Maria Pia Amato, Prof

Targeting Subclinical Motor and Cognitive Impairment in Patients With Early Onset Multiple Sclerosis

Our project proposal is based on an individualized rehabilitation approach in patients with early stage relapsing remission (RR) MS. This approach will be based on risk stratification obtained using several clinical and demographic parameters that are not commonly used in clinical practice. This risk score will be obtained from an …

18 years of age All Phase N/A
S Sasitorn Kittivoravitkul, Ph.D

Drospirenone (3 mg) + Ethinyl Estradiol (0.02 mg) Tablets Relative to Yaz®

The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose. The study will be randomized, open-label, single dose, two way crossover design with two-period, two-treatment and two-sequence under fasting condition and at …

18 - 55 years of age Female Phase 1

The Role of Traditional Music Therapy on Burnout Syndrome Among Healthcare Workers: Psycho-Neuro-Immuno-Endocrine Aspects

The goal of this clinical trial study is to learn about the role of traditional music therapy on burnout syndrome among healthcare workers, based on psychology, neurology, immunology, and endocrinology aspects. The main questions it aims to answer are : How traditional music therapy can improve psychological aspects (emotional exhaustion, …

18 - 60 years of age All Phase N/A
T Theodoros Kelesidis, MD, PhD, Msc

Mitoquinone/Mitoquinol Mesylate as Oral and Safe Postexposure Prophylaxis for Covid-19

Adults who do not have major health, kidney, gastrointestinal disease will be randomized to receive oral mitoquinone/mitoquinol mesylate (Mito-MES) versus placebo to prevent the development and progression of COVID-19 after high-risk exposure to a person with confirmed SARS-CoV-2 infection.

18 - 65 years of age All Phase 2
M Maria Jose DeLosSantos, PhD

Efficacy of Oocyte Activation With Two Types of Ca2+ Ionophore.

This study is a prospective ranzomized analysis including 372 human oocytes from 44 women. Half of the oocytes from the same patient will be randomly allocated to induce oocyte activation using two protocols: in protocol nº 1 we will use ionomycin (prepared solution), protocol nª2 A23187 (GM508 CultActive Gynemed) will …

years of age Female Phase N/A

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