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Minatoga, Japan Clinical Trials

A listing of Minatoga, Japan clinical trials actively recruiting patients volunteers.

Found 65,447 clinical trials
G Giselle Singer

Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomy

Keloids are common, benign cutaneous overgrowths that manifest clinically as raised, hypertrophic, often hyperpigmented lesions which are formed in response to dermal injury or idiopathic stimuli. Although keloids are a common disease, it's exact incidence and prevalence is not known. Despite the debilitating nature of keloids, current treatment modalities are …

18 years of age All Phase 2

Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART

In summary, there is a compelling rationale for investigating venetoclax as an intervention to sensitise virus-expressing cells to apoptosis and thereby reduce the size of the latent HIV reservoir. While this concept may ultimately need to be tested in the setting of concomitant latency reversal, the investigators propose to initially …

18 - 65 years of age All Phase 1/2
S Susanne Fischer, PhD

Whole-body Hyperthermia for Depression

The goal of this clinical trial is to test the efficacy of whole-body hyperthermia in major depression. The main question it aims to answer is: • Does whole-body hyperthermia alleviate symptoms of depression? Participants will be randomised to sham or active whole-body hyperthermia. The study will last 6 weeks during …

18 - 65 years of age All Phase N/A

Protective VEGF Inhibition for Isotoxic Dose Escalation in Glioblastoma

Glioblastoma is the most aggressive brain tumor and often recurs locally despite intensive treatment. Standard chemoradiotherapy with 60 Gy may not be sufficient to control the tumor, and dose escalation seems to be warranted, but causes more toxicity. To address this, the multicentric PRIDE trial employs two cycles of bevacizumab …

18 - 70 years of age All Phase 2
X Xingen Zhu, Prof

Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK)

The LD-ITUK is a multicenter, prospective, randomized, double-blind, blind endpoint, placebo-control design trial. All eligible patients with the diagnosis of severe aSAH will be randomly assigned to the treatment group or the placebo group. Patients in the treatment group will receive standard treatment with the addition of lumbar drainage combined …

18 years of age All Phase 4
M Mette Cathrine Ørngreen, MD, DMSc

Whole Body Metabolism in Children Before and After Treatment of CNS Tumor

At the center of pediatric oncology in Copenhagen the investigators experience that the children with brain tumor, more or less have a healthy body with normal skeletal muscle mass and are physical active to the same level as their friends at the same age. The treatment period for brain tumor …

6 - 18 years of age All Phase N/A
J Jonathan D Boone, MD

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

This study evaluates how lifestyle modifications that may be made to manage chemotherapy side effects in patients with gynecologic malignancies.

35 - 70 years of age Female Phase N/A

TSN222 in Subjects With Advanced Solid Tumors or Lymphomas

The study is a first-in-human [FIH], open-label phase 1/2 study of TSN222 in subjects with advanced solid tumors or lymphomas. This study is comprised of a Phase 1 dose escalation and Phase 2 dose expansion component.

18 years of age All Phase 1/2
T Thomas Sullivan

Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty

The purpose of this study is to compare two different antibiotic regimens and techniques during total ankle arthroplasty (TAA). Primary Objective: Comparable levels of vancomycin will be found in bone, soft tissue, and systemic samples between patient groups. Secondary Objective: Compare 30 day and 90 day post-operative complication rates (infection) …

18 years of age All Phase 4
X Xianghua Huang, MD

Daratumumab for Patients With Light Chain Amyloidosis

This is a prospective, single-center study exploratory clinical trial, aim to exploring the efficacy and safety of daratumumab in patients with AL amyloidosis, patients were divided into three groups: one group received long-term treatment with daratumumab based regimen, and the other group received autologous stem cell transplantation after two standard …

18 - 75 years of age All Phase N/A

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