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Trento, Italy Clinical Trials

A listing of Trento, Italy clinical trials actively recruiting patients volunteers.

Found 21 clinical trials
M Michela Coccia, MD

Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS

Phase II/III multicenter, randomized, double-blind, placebo-controlled trial on acetyl-L-carnitine (ALCAR) in subjects living with amyotrophic lateral sclerosis (ALS). Primary study aim: The clinical objective consists of assessing the efficacy of ALCAR (two different dosages will be tested: 1.5g/day and 3g/day) on the progression of functional disability (loss of self-sufficiency), as …

18 years of age All Phase 2/3
S Stefania Campostrini, Mac

TMS-related Measures as Biomarker of Cognitive Impairment in PD

The goal of the present study is to explore the diagnostic and prognostic value of neurophysiological biomarkers obtained through paired-pulse Transcranial Magnetic Stimulation (TMS) techniques in individuals affected by Parkinson's disease (PD) with and without cognitive decline. The main questions it aims to answer are: TMS measures of cortical excitability …

18 years of age All Phase N/A
E Elena Rossato

Severe Acquired Brain Injuries: Prognostic Factors and Quality of Care

The main purpose of this project is to identify the medium-term prognostic factors for patients with Severe Acquired Brain Injuries and evaluate their impact. The secondary aim is to create a system of continuous assessment of the quality of care for each rehabilitation unit.

18 years of age All Phase N/A
M Marco Carbone, MD

National Database on Primary Biliary Cholangitis

Primary biliary cholangitis (PBC) is a rare, autoimmune, cholestatic liver disease. No data about the disease epidemiology exist in Italy. Therefore this study aims to develop a national PBC patient database linked to a biological sample storage.

18 years of age All Phase N/A
M Maartin Metzelder

Role of Preoperative D-dimer Levels in the Diagnosis of Adnexal Torsion

Adnexal torsion is the fifth most common gynecologic emergency. Thirty percent of all cases of adnexal torsion occur in females younger than 20 years. Approximately 5 of 100,000 females aged 1-20 years are affected, with girls older than 10 years at increased risk because of hormonal influences and gonadal growth …

- 17 years of age Female Phase N/A
S Sergio Baldari

Protocol ITANET - Registry

This is a prospective observational study with the aim to create an Italian database for the collection of data on diagnostic approach, therapy and follow up of patients affected by GEP-NET (gastro-enteric-pancreatic neuroendocrine tumours). Data for approximately 200 italian patients were already previously collected in the ENETS database (international database). …

18 years of age All Phase N/A
U Ugo de Giorgi, MD

PRostate Cancer Plasma Integrative Multi-modal Evaluation

The study aims to develop PRIME (PRostate cancer plasma Integrative Multi-modal Evaluation) liquid biopsy test and to implement its use to query prospectively collected samples in advanced prostate cancer (PCa) clinical trials and/or clinical settings. In order to maximise the utility of liquid biopsies for advanced PCa, PRIME is focused …

18 years of age Male Phase N/A

BRING-UP 3 Heart Failure

The aim of this observational study is to assess the level of adherence to guideline recommendations regarding the management of patients with Heart Failure with Reduced Ejection Fraction (HFrEF); - the safety profile of the implementation of recommended treatments; - to monitor treatment patterns of patients with acute hert failure …

18 years of age All Phase N/A
L Lorenzo Crepaz

ACute Treatment of Incisional Ventral Hernia

This observational, retrospective study aims to examine surgical outcomes in non-elective surgery for incisional hernia. The main questions it aims to answer are: 30-day morbidity short- and long-term surgical outcomes Data will be retrospectively collected from participating centers and compared. Researchers will compare surgical outcomes of the minimally invasive and …

18 - 80 years of age All Phase N/A
S Simone Beretta, MD, PhD

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest

Status epilepticus (SE) is found in 20-30% of patients in coma after cardiac arrest, is often refractory to medical therapy and is considered a negative prognostic factor. Intensity and duration of treatment of refractory and super-refractory post-anoxic SE pose the ethical dilemma between futility of treatments and, conversely, their premature …

18 years of age All Phase N/A

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