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San Donato Milanese (MI), Italy Clinical Trials

A listing of San Donato Milanese (MI), Italy clinical trials actively recruiting patients volunteers.

Found 925 clinical trials
A Antonio Mangieri, MD

Timing And Typology of ConducTIon disturbanCes During TAVI

The TACTIC-TAVI registry aims to collect information about a consecutive cohort of patients undergoing transcatheter aortic valve insertion. The registry is international, multi-centre and observational. The registry is planned to continue until the calculated sample size is achieved.

18 years of age All Phase N/A
L Luca Valvassori, MD

Rescue Stenting and Intravenous Thrombolysis in Patients with Large Vessel Ischemic Stroke

Intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are the standard of care for treating selected patients with acute large-vessel occlusion stroke (LVOS). Successful revascularization is strongly correlated with favorable outcomes. Nevertheless, recanalization failure with stent retrieval and contact aspiration has been observed in up to 29% of patients. If primary …

18 years of age All Phase N/A
A Alberto Doretti, MD

OnaBotulinumtoxin-A in Chronic Migraine Patients with Short or Long Disease History (the BACH Study)

The goal of this observational prospective multicentric study, 12 months duration is to investigate whether the history of Chronic Migraine and, more precisely, its duration for over or less than 10 years, can predict OBT-A treatment effectiveness. Since CM patients may have a complex psychopathological profile and psychiatric symptoms represent …

18 - 70 years of age All Phase N/A
C Claudia Saradeno, PHD

Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease

Clinical diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) is challenging, especially in the early stages. Each disease is associated with distinct conformers of misfolded alpha-synuclein (maS) which form typical protein aggregates in the brain and represent key disease biomarkers. Thus, detection and …

years of age All Phase N/A
G Gabriela Felipe

Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer

This is a multicenter retrospective observational study aimed to evaluate the prevalence of osteo-metabolic complications in patients with thyroid cancer.

18 years of age All Phase N/A
S Silvio Danese, MD

Evaluation of an Anti-TREM-1 Treatment on an ex Vivo Human Intestinal Model

TIME is an observational study performed on UC and CD patients under endoscopic surveillance for monitoring the clinical activity of their disease. The main objective of the study is to confirm the therapeutic potential of TREM-1 in inflammatory bowel disease.

18 - 60 years of age All Phase N/A
M Massimo Piepoli, MD, PhD

Functional Capacity in Anderson-Fabry Disease Patients

The goal of this observational study is to observe the relation between excercise parameters - assessed by CPET - and rest/stress hemodynamic parameters - assessed by echocardiogram and CMR - in patients with a genetic diagnosis of Anderson-Fabry Disease. Participants will undergo: baseline evaluation: clinical evaluation, disease staging with FASTEX …

years of age All Phase N/A
E Elisa Canu, PhD

Speech and Language Interventions for Italian People With PPA

Primary progressive aphasia (PPA) is an umbrella term used to refer to several clinical variants that manifest as an insidious deterioration of speech/language skills, usually due to frontotemporal lobar degeneration and/or Alzheimer's disease. Consensus criteria have been proposed by an international community regarding the sub-classification of PPA into three variants: …

40 - 85 years of age All Phase N/A
E Elena Mauro, MD

Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases.

General aim of the study is the improvement of the clinical knowledge of ultra-rare inherited metabolic and degenerative neurological diseases (prevalence less than 5:100,000) in adulthood through the systematic longitudinal collection of clinical, laboratory and instrumental data.

18 years of age All Phase N/A
F Francesca Mameli

Genetics in Parkinson's Disease: Behavioral and Cognitive Outcomes

The genetic landscape of Parkinson's disease (PD) is characterised by rare high penetrance pathogenic variants causing familial disease, genetic risk factor variants driving PD risk in a significant minority in PD cases and high frequency, low penetrance variants, which contribute a small increase of the risk of developing sporadic PD. …

18 years of age All Phase N/A

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