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Tzrifin, Israel Clinical Trials

A listing of Tzrifin, Israel clinical trials actively recruiting patients volunteers.

Found 329 clinical trials

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

The goal of this first-in-human clinical trial is to assess the safety and tolerability of four doses of a new study drug called VO659 in people with genetic disorders called spinocerebellar ataxia type 1, type 3 or Huntington's disease. Another aim is to determine the concentrations of the study drug …

25 - 60 years of age All Phase 1/2
S Shachar Finci, MD

Hyperbaric Oxygen Therapy for Men Suffering From Infertility Due to Oligospermia.

Infertility in a couple is defined as the inability to achieve conception despite one year of frequent, unprotected intercourse. Infertility affects approximately 12% of couples attempting to conceive. The goal of this study is to explore the potential beneficial effect of HBOT on sperm count of infertile male due to …

21 years of age Male Phase N/A
I Iris Gluck, MD

A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC

A unique combinational treatment for cancer employing intratumoral diffusing alpha radiation emitter device with check point inhibitor for recurrent unresectable or metastatic Head and Neck Squamous Cell Carcinoma

18 years of age All Phase N/A
Y Yara Agbaria, MSc

The Impact of THC on Pain Modulation in Fibromyalgia

The objective of this cross-sectional, double-blind, placebo-controlled clinical trial is to enhance our understanding of the pain modulation mechanisms in females diagnosed with Fibromyalgia syndrome (FMS). This study is designed to address several key questions: Is there a discernible difference in the effectiveness of the two prevalent pain modulation approaches, …

20 - 60 years of age Female Phase N/A

Tranexamic Acid During Colonic Endoscopic Resection Procedures

Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on …

18 years of age All Phase 4

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

The main objective of this study is to evaluate the feasibility and safety of the GEMINUS system in patients with severe symptomatic aortic stenosis. This is a prospective, open label, multicentre, single arm, first in human clinical study. Clinical follow up for all patients will be performed at 30 days, …

18 - 120 years of age All Phase N/A
M Moshe Phillip, Prof

Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy

The Proposed study is a double blind, randomized, placebo controlled study The aim of the study is to evaluate the effect of combined Growth Hormone (GH) treatment & nutritional formula supplementation versus GH & placebo on growth parameters in 64 children with Isolated Growth Hormone Deficiency (IGHD) after the 2nd …

3 - 14 years of age All Phase N/A

Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery

Cefazolin is given routinely pre and intraoperatively for patients undergoing spinal surgery to reduce the rate of infection. Intra-wound admission of Vancomycin powder has been suggested to reduce wound infection rates. Therefore, this study aims to compare the rate of wound-related complications between patients receiving standard treatment compared to patients …

18 - 90 years of age All Phase 3
M Moshe Phillip, Prof

The Effect of Nutritional Formula Supplementation on Linear Growth of Growth Hormone (GH) Treated Prepubertal Children With Idiopathic Short Stature (ISS) After 2 Years From the Beginning of GH-therapy

The proposed study is a double blind, randomized, placebo controlled study. The aim of the study is to evaluate the effect of combined growth hormone (GH) treatment &nutritional formula supplementation versus GH & placebo on growth parameters in 64 children with Idiopathic Short Stature (ISS) after the second year of …

5 - 10 years of age All Phase N/A
M Moshe Yeshurun

Combined Kidney and Hematopoietic Stem Cell Transplantation for Tolerance Induction

Combined transplantation of kidney and bone marrow between HLA-matched sibling donor-recipient pairs to induce immune tolerance in order to enable complete discontinuation of immunosuppressive therapy without kidney rejection. Hematopoietic stem cells are collected from the donor 4 to 8 weeks before kidney transplantation, CD34 cells are enriched by positive selection …

18 - 65 years of age All Phase 2

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