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Rishon Le Zion, Israel Clinical Trials

A listing of Rishon Le Zion, Israel clinical trials actively recruiting patients volunteers.

Found 393 clinical trials
J Jair Bar, MD-PhD

Neo-Bio-ADAURA: a Phase II Study to Evaluate Mechanisms of Resistance to Neoadjuvant Osimertinib

This study is a single-arm phase II study of neoadjuvant osimertinib as monotherapy for the treatment of patients with resectable stage II-III non-small cell lung cancer (NSCLC) harboring an epidermal growth factor receptor (EGFR) sensitizing mutation (L858R or deletion in exon 19 [Ex19del]).

18 years of age All Phase 2
G Gal Strauss

A Study of BND-35 in Participants With Advanced Solid Tumors

This is an open-label, multicenter, dose escalation and dose optimization study designed to evaluate safety, tolerability and preliminary anti-tumor activity of BND-35 administered alone and in combination with nivolumab or with cetuximab. The study will enroll advanced cancer patients with unresectable or metastatic disease who are refractory to or are …

18 years of age All Phase 1
Y Yoav Gimmon, PT, Ph.D

App-supported Vestibular Rehabilitation (RCT)

A randomized controlled trial to assess the efficacy of an app-assisted vestibular rehabilitation in increasing adherence to VR and treatment outcomes

18 years of age All Phase N/A

Observational Study of Adult Participants With Diabetic Macular Edema and Suboptimal Response to Anti-Vascular Endothelial Growth Factor Treated With Dexamethasone Intravitreal Implant

The dexamethasone 700 μg intravitreal implant (DEX-I) delivers dexamethasone gradually to the retina over time. It is an approved drug for the treatment of DME. This study will assess adult participants with diabetic macular edema (DME) and suboptimal response to anti-vascular endothelial growth factor therapy that are treated with DEX-I …

18 years of age All Phase N/A

A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

WAYFIND-R is a registry that aims to capture high-quality real-world data linking next-generation sequencing, treatments and outcomes from cancer patients diagnosed with a solid tumour. The WAYFIND-R has three main overarching objectives: 1. To provide a platform to support the design and conduct of clinical and epidemiological research; 2. To …

18 years of age All Phase N/A
A Avner Cohen, Prof

Screening for Islet Autoantibodies in the Israeli Paediatric General Population for Detection of Pre-symptomatic Type-1 Diabetes Mellitus

A national screening program for children aged 9-18 months that will be tested for the presence of islet autoantibodies.Up to 50,000 Children will be screened by their primary care physician all over Israel. The initial screening will be done at the age of 1 year (in conjunction with the routinely …

9 - 18 years of age All Phase N/A
L Liran Statlender

Pictorial Fit-Frail Scale in Adults Admitted to the ICU in a Tertiary Center- an Observational Prospective Study

Understanding the frailty levels of critically ill patients using the PFFS at time of admission to ICU. Exploring any associations between frailty, other prognostic factors, and patient outcomes.

60 years of age All Phase N/A
R Reut Moran, MsC

MR Imaging Study of TBI in Children

This project will combine the data collected from structural and functional MRI scans and neuropsychology performance post-TBI in children. Patients will be followed for a year, in order to examine the brain and cognitive recovery post head injury.

9 - 18 years of age All Phase N/A
O Ofer Havakuk, MD

Conservative Management of Left Ventricular Assist Device Candidates

Left ventricular assist device (LVAD) candidates will be comprehensively evaluated at our center, including clinical evaluation, echocardiography, right heart catheterization, cardiopulmonary exercise test and laboratory exams. following this evaluation, patients will be treated with inotropes, diuretics, uptitrated neurohormonal therapy. vitamin and iron deficiencies will be corrected and the patients will …

18 - 80 years of age All Phase N/A
Y Ygal Rotenstreich, MD

Determination of Physical Parameters Relevant to Ophthalmic Lasers

The use of lasers in medicine in general, and diagnosis and treatment in ophthalmology in particular, increased significantly. Making retinal surgery using lasers have become increasingly common. The goal: to diagnose eye diseases safely

18 - 40 years of age All Phase N/A

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