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Rishon Le Zion, Israel Clinical Trials

A listing of Rishon Le Zion, Israel clinical trials actively recruiting patients volunteers.

Found 368 clinical trials

Tranexamic Acid During Colonic Endoscopic Resection Procedures

Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on …

18 years of age All Phase 4
T Tehila Belfer

Efficacy and Safety of AqueousJoint Intra-Articular Injections in Mild to Moderate Knee Osteoarthritis

The goal of this clinical trial is to evaluate the Efficacy and Safety of AqueousJoint Intra-Articular Injection in Mild to Moderate Knee Osteoarthritis of AqueousJoint. The main questions it aims to answer are: To demonstrate superior efficacy of AqueousJoint administered via intra-articular injection versus placebo during the study period. To …

30 - 85 years of age All Phase N/A
K Karin Elman Shina, MD

Hyperbaric Oxygen Therapy for Prodromal Alzheimer´s Disease With Cerebrovascular Disease

Alzheimer´s disease is a devastating illness that effects the patients as well as their family members. Its prevalence increases exponentially and the burden on the healthcare system is enormous. AD neuropathology begins 15-20 years before the occurrence of cognitive symptoms, which ranges from preclinical stage to mild cognitive impairment (MCI) …

60 - 85 years of age All Phase N/A
Y Yara Agbaria, MSc

The Impact of THC on Pain Modulation in Fibromyalgia

The objective of this cross-sectional, double-blind, placebo-controlled clinical trial is to enhance our understanding of the pain modulation mechanisms in females diagnosed with Fibromyalgia syndrome (FMS). This study is designed to address several key questions: Is there a discernible difference in the effectiveness of the two prevalent pain modulation approaches, …

20 - 60 years of age Female Phase N/A
M Moshe Yeshurun

Combined Kidney and Hematopoietic Stem Cell Transplantation for Tolerance Induction

Combined transplantation of kidney and bone marrow between HLA-matched sibling donor-recipient pairs to induce immune tolerance in order to enable complete discontinuation of immunosuppressive therapy without kidney rejection. Hematopoietic stem cells are collected from the donor 4 to 8 weeks before kidney transplantation, CD34 cells are enriched by positive selection …

18 - 65 years of age All Phase 2
M Moshe Phillip, Prof

Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy

The Proposed study is a double blind, randomized, placebo controlled study The aim of the study is to evaluate the effect of combined Growth Hormone (GH) treatment & nutritional formula supplementation versus GH & placebo on growth parameters in 64 children with Isolated Growth Hormone Deficiency (IGHD) after the 2nd …

3 - 14 years of age All Phase N/A

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

The main objective of this study is to evaluate the feasibility and safety of the GEMINUS system in patients with severe symptomatic aortic stenosis. This is a prospective, open label, multicentre, single arm, first in human clinical study. Clinical follow up for all patients will be performed at 30 days, …

18 - 120 years of age All Phase N/A

The Role of Microbiome in Recurrent Obesity Before and After Antibiotic/Placebo Treatment

This past century witnessed a significant increase in the prevalence of obesity. Successful weight loss maintenance is defined as losing at least 10% of the initial body weight and maintaining it for at least one year. However, keeping a low body weight is rarely maintained, as 80% of people who …

18 - 65 years of age All Phase N/A
O Ophir Freund, MD

Cardiovascular Assessment During COPD Exacerbation to Improve Diagnosis and Treatment

This is a research study involving patients hospitalized for COPD flare-ups. Patients will be randomly assigned to two groups: one group will only see a pulmonologist (lung doctor), and the other group will also be seen by a cardiologist (heart doctor) during their hospital stay. Both groups will fill out …

18 - 75 years of age All Phase N/A
S Shiri Sherf-Dagan, PhD

Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events

The goal of the study is to evaluate the effect of nutrition intervention on gastrointestinal symptoms, treatment discontinuation rate, nutritional parameters (e.g., dietary intake and eating habits), anthropometric measures, functional parameters, and QOL during the initiation and up-titration phase of incretin-based Anti Obesity Medications (AOM) treatment in patients with overweight/obesity. …

18 years of age All Phase N/A

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