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Queen Mary Hospital, Hong Kong Clinical Trials

A listing of Queen Mary Hospital, Hong Kong clinical trials actively recruiting patients volunteers.

Found 595 clinical trials
M Meizhen Huang, PhD

Powering Up Stroke Rehabilitation Through HIIT

Objectives: To investigate the effects of high-intensity interval training (HIIT) on musculoskeletal fitness in chronic stroke survivors. Hypothesis to be tested: HIIT, performed on a recumbent stepper, will significantly enhance muscle power in chronic stroke survivors when compared with moderate-intensity continuous training (MICT) Design and subjects: Assessor-blinded, stratified, randomised, placebo-controlled …

50 - 80 years of age All Phase N/A
S Sau Lan Tsang, PhD

Neurophysiological Changes After Perturbation-based Training in Older Adults

This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group. Changes in postural stability and neurophysiology in the brain following PBT compared to walking exercise without perturbation will be investigated.

60 years of age All Phase N/A
W Wayne LS Chan, PhD

Effects of Step Training in Older Adults with Mild Dementia

Step training has been shown to be effective at reducing the incidence of falls and improving related risk factors, including choice stepping, in healthy older adults. However, the effects of step training have not been investigated in OWMD. The primary objective of the proposed project will be to assess the …

65 years of age All Phase N/A
G Gary Kui-Kai LAU

Instant Message-delivered Early Psychological Intervention in Stroke Family Caregivers

Psychological distress including depression and anxiety is a major component of caregiver stress, and its negative impact on caregivers' health and well-being has been established in the literature. A recent meta-analysis reported the prevalence of depression and anxiety in stroke caregivers as 40.2% and 21.4% respectively. An evidence profile report …

18 years of age All Phase N/A
C Christopher LEUNG

Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients

The goal of this clinical trial is to determine whether oral supplementation with different nicotinamide adenine dinucleotide (NAD) precursors can improve visual function in adults with primary open-angle glaucoma. The main questions it aims to answer are: Does daily oral administration of equimolar doses of nicotinamide riboside (NR), nicotinamide (NAM), …

18 years of age All Phase 2
Y Yuliang Wang, Mphil

Individualized Alpha Neurofeedback for ADHD

Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders, characterised by inattention, hyperactivity, and impulsivity. Although pharmacotherapy is considered the first-line treatment for ADHD at all ages (at least for severe cases), non-pharmacological therapies might be equally effective without the risk of drug side effects. Some …

5 - 13 years of age All Phase N/A
O Oscar Leung, MSocSc

rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT

This RCT aims to investigate the effect of repetitive transcranial magnatic stimulation (rTMS) in treating children with hemiplegoc cerebral palsy. The study will measure any improvement in spasticity after using contra-lesional inhibitory rTMS follow by intensive limb training. Participants will attend a 10-day rTMS treatment sessions, follow by intensive training …

7 - 18 years of age All Phase N/A
H Hon Chi Yip, FRCSEd

Perioperative FLOT vs Adjuvant XELOX for CA Stomach

This is a single centre randomised controlled trial, comparing perioperative FLOT versus adjuvant XELOX for locally advanced gastric and esophagogastric junction cancers. Patients with operable clinical T3 or above and N1 or above gastric and esophagastric junction cancer would be recruited. Participants would be randomised to perioperative FLOT versus adjuvant …

18 years of age All Phase 3
V Vincent Wong, MD

Development of a FibroScan Liver Examination Using a Single Probe

This is an exploratory, international, prospective, interventional, multicenter clinical investigation that will take place in 1 Hong Kong site and 3 French sites and 309 adults patients will be included. The study objective is to assess the LSM reproducibility between the FibroScan examination performed with the Single Probe (SP) and …

18 years of age All Phase N/A
S Stanley SC Wong, MBBS

Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty

Total knee arthroplasty is a commonly performed orthopaedic surgery for the treatment of end-stage osteoarthritis when conservative management becomes ineffective. TKA is associated with significant acute postoperative pain and many patients experience severe postoperative pain despite the use of multimodal analgesia. Poor acute postoperative pain control impacts rehabilitation, prolongs recovery …

18 - 80 years of age All Phase 3

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