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Lai Chi Kok, Hong Kong Clinical Trials

A listing of Lai Chi Kok, Hong Kong clinical trials actively recruiting patients volunteers.

Found 598 clinical trials
D David SC Hui, MD

To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong

This study aims to prospectively assess the asthma control and management of asthma patients who are on step 4, 5 asthma of GINA in Hong Kong (on at least medium-dose ICS-LABA as controller therapy for asthma) and also observe their exacerbations over 2 years. In addition, this study will also …

18 years of age All Phase N/A
K Karlen Ka Pui Law, M. Phil

Proprioceptive Deficits in Degenerative Cervical Myelopathy

Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control. DCM usually presents with body incoordination, hand clumsiness and gait disturbance associated with proprioceptive dysfunction that hinders the physical performance and functions. In this study, …

50 years of age All Phase N/A
M Mandy Yu, MPH

Prodromal Markers in Recurrent Dream Enactment Behaviors Without REM Sleep Without Atonia

REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and REM sleep without atonia (RSWA) during polysomnographic assessment, with a male predominance and typical onset age at early 60's. The majority of patients with idiopathic RBD (iRBD) will eventually develop α-synucleinopathy, for …

45 - 65 years of age All Phase N/A
Y Yuen Kwan Agnes Lai, PhD

Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment

Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and potentially lead to cardiometabolic and neurocognitive sequelae. Chronic intermittent hypoxia, sleep fragmentation of OSA, and insufficient sleep have been significantly associated with higher risks …

50 - 80 years of age All Phase N/A
M Mandy Yu, MPH

Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior Disorder

REM sleep behavior disorder is a novel and distinct parasomnia characterized by recurrent dream enactment behaviors (DEBs) and polysomnographic features of REM sleep without atonia (RSWA), with typical onset age at early 60's. Idiopathic RBD (iRBD) has been suggested as a most specific precursor of α-synucleinopathy-related neurodegeneration (e.g. Parkinson's disease …

40 - 65 years of age All Phase N/A
C Chi Fai NG, MD

Patient and Physician Benefit/ Risk Preferences for Treatment of mPC in Hong Kong: a Discrete Choice Experiment

The objective of this study is to examine the preference weightings in term of risk/ benefit attributes of treatment in physician and prostate cancer patients from different stages of disease.

18 years of age Male Phase N/A
P Pui Wah Jacqueline Chung, MBBS

Transcriptome Profiling and Endometrial Receptivity

The aim of this study is to correlate and identify the biochemical markers which may reflect WOI. Blood samples will be collected and endometrial biopsy will be performed at particular time points.

20 - 40 years of age Female Phase N/A
B Brigette MA, MD

PRecision Oncology CUhk pRogrammE (PRO-CURE)

The main aim of this project is to establish an innovative model of a comprehensive precision oncology platform to help individualizing drug therapy for patients with advanced cancers at The Chinese University of Hong Kong. The other objectives include to optimize the genomic matching and access of patients with unique …

18 - 75 years of age All Phase N/A
W Winston WS Shing, MBBS

Pharmacokinetics of Apixaban in Peritoneal Dialysis

Atrial fibrillation (AF) is fairly prevalent in patients with end stage renal disease (ESRD) with the prevalence estimated to be 3.8 - 27%. While it is reported that patient with peritoneal dialysis (PD) has a lower incidence of AF as compared to patient with haemodialysis (HD), the risk is still …

18 - 80 years of age All Phase N/A
Y Yuen Kwan Agnes Lai, PhD

Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment

Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive sequelae. Chronic intermittent hypoxia, sleep fragmentation of OSA, and insufficient sleep have been significantly associated with higher risks of …

18 years of age All Phase N/A

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