Haidari, Greece Clinical Trials

The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination

Four groups of patients with type 2 diabetes mellitus with high or very high cardiovascular risk or heart failure with preserved ejection fraction (HFpEF) will be studied before and at 6 and 12 months of treatment: 60 patients treated with a combination of GLP1 analogue and SGLT2 inhibitor ± metformin …

EndotyPIng PreHospitAl de Novo Acute hYpoxemic Respiratory Failure

We attempt to perform dynamic endotyping of critically ill patients presenting in the emergency department with de novo acute hypoxemic respiratory failure (AHRF). We also attempt to identify what clinical, radiological, physiological and biological variables collected early in the course of AHRF correlate with subsequent mortality and/or persistent severe hypoxemia.

C Chryssoula V Staikou, MD

Postoperative Relapses in MS Patients

The aim of the study is to record any relapses during one year postoperatively in patients and parturients diagnosed with MS who received general or regional anesthesia

S Site Contact

Real-world Usage of HyQvia in Multiple Myeloma Adults With Secondary Immunodeficiency

In this study, multiple myeloma participants with secondary immunodeficiency (SID) will be treated with HyQvia according to their clinic's standard practice. The study's main aim is to look into infusion parameters of HyQvia administration.

S Stergios A Polyzos, PhD

Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)

A 24-month prospective, open-label, randomized, multicenter, multinational, non-inferiority pragmatic clinical trial evaluating zoledronate single or double infusion versus oral alendronate following denosumab

E Elena Fountzilas, MD

Real-world Data in Patients With Breast Cancer Treated With Abemaciclib

The present study will assess real-world clinical outcomes and adverse events from treatment with endocrine therapy combined with abemaciclib in patients with HR-positive, HER2-negative advanced breast cancer.

Lifetech CeraFlex™ ASD Closure System Post-Market Clinical Follow-Up

The objective of this post-market registry is to assess the clinical use of the Lifetech CeraFlex™ Closure System in a real-world and on-label fashion.

Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study

This study is a single-country, non-interventional, multicenter, observational study, mainly based on primary data collection to assess the effect of ofatumumab on clinical parameters of Multiple Sclerosis (MS) in a routine medical care setting, as compared to the standard of care (SoC) arm of a closely monitored phase-IIIb study (STHENOS, …

F Fotios Skoufis, MD Medicine

Role of Tryptase Levels in Patients With Stable Coronary Artery Disease.

The aim of this study is to measure the levels of serum tryptase and correlate them with the severity of coronary artery disease in study population. In addition, it will evaluate the usability of tryptase levels as a prognostic biomarker for future cardiovascular events.

E Evangelos Giamarellos-Bourboulis, MD,PhD

Viscoelastic Coagulation for Early Sepsis Detection

The goal of this observational study is to investigate whether selected variables of coagulation measured by Viscoelastic Coagulation Monitoring (VCM) can serve as early predictors of progression to sepsis in adult patients presenting to the emergency department (ED) with suspected infection. The main questions it aims to answer are: Can …