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Frankenberg, Germany Clinical Trials

A listing of Frankenberg, Germany clinical trials actively recruiting patients volunteers.

Found 68 clinical trials
W Winfried Rief, Prof. Dr.

Enhancing Treatment Outcomes: The Impact of Physical Touch in Back and Neck Pain Management

In this study, we aim to investigate the impact of professional touch techniques on treatment expectations and adherence in German-speaking adults with current back or neck pain. Participants will engage in a 45-minute interaction, including structured components and physical touch interventions. We will assess treatment expectations, treatment effects, adherence, and …

18 - 100 years of age Both Phase N/A
A Alexander Otto König, PD Dr.

A Trial of Cabozantinib in Patients With Advanced, Low Proliferative NEN G3

The main objective of this clinical trial represents the evaluation of efficacy of the tyrosine kinase inhibitor Cabozantinib in patients with NEN G3 with a proliferation rate of Ki67 20 - 60%.

18 - 100 years of age Both Phase 2
C Christoph Vogelbacher, Dr.

Combined N-of-1 Trials to Assess Open-Label Placebo Treatment for Antidepressant Discontinuation Symptoms

It has been widely recognized that the placebo effect has a profound impact on treatment outcome in many different conditions. Recent studies imply that this effect appears even if placebos are openly administered; so called "open-label placebos" (OLP). Compelling evidence suggests the efficacy of OLP in the treatment of pain …

18 - 100 years of age Both Phase N/A

Feasibility of an Online Modeled Exposure in Spider Fearful Individuals

The effectiveness of an optimized group exposure treatment is investigated in spider-fearful individuals. Participants will undergo an optimized standardized exposure treatment. After receiving information about the treatment and the phobic stimulus (spider) through a psychoeducation video, participants will observe an exposure treatment of another fearful person, either live or by …

18 - 100 years of age Both Phase N/A
M Matthias Reinhard, Dr.

A Comparison of Two Psychotherapy Programs in Persistently Depressed Treatment-Resistant Inpatients

The purpose of this study is to compare the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) conducted over 16 weeks (acute and continuation treatment) with Behavioral Activation (BA; same dose and duration) in persistently depressed treatment-resistant inpatients regarding efficacy, moderators and mediators of change.

20 - 70 years of age Both Phase N/A
K Kathrin Schubert, M.Sc.

Efficacy of Internet-based Cognitive Behavioral Therapy for Endometriosis

The purpose of this study is to evaluate the efficacy of an internet-based cognitive behavioral therapy in reducing the impairment caused by endometriosis.

18 - 45 years of age Female Phase N/A
A Anke Haberkamp, PhD

Gamification in the Treatment of Spider Phobia

Mobile applications are more and more considered when implementing programs for treating mental disorders. The study aims to reduce avoidance and fear of spiders in spider-fearful individuals by combining exposure principles with gamification elements (e.g. narrative background, level progression, points, feedback). We investigate the efficacy of the gamified app in …

18 - 65 years of age Both Phase N/A
U Ulrich Schu, MD

Enoxolone in Major Depression - Biomarker-outcome Relationship

Many different forms of depression exist. It is difficult to predict to what treatment a given patient with depression responds. Studies demonstrate that biomarkers can help to distinguish different forms of depression. Simple markers, like aldosterone/cortisol in body fluids, blood pressure and inflammation markers , have been identified as predictors …

18 - 100 years of age Both Phase 1/2

Allogeneic Stem Cell Transplantation vs. Conventional Therapy as Salvage Therapy for Relapsed / Progressive Patients With Multiple Myeloma After First-line Therapy

Allogeneic stem cell (allo SCT) transplantation for multiple myeloma is a potential curative treatment, but is associated with morbidity and treatment related mortality. Approved drug combinations or another autologous stem cell transplantation (auto-SCT) can be used for relapsed patients resulting in a median progression free survival up to 2-3 years. …

18 - 70 years of age Both Phase 3
O Omid Madadi-Sanjani, Dr.

Mucous Fistula Refeeding Reduces the Time From Enterostomy Closure to Full Enteral Feeds ("MUC-FIRE" Trial)

The primary objective of this study is to demonstrate that mucous fistula refeeding between enterostomy creation and enterostomy closure reduces the time to full enteral feeds after enterostomy closure compared to standard of care.

- 12 years of age Both Phase N/A

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