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Berlin - Spandau, Germany Clinical Trials

A listing of Berlin - Spandau, Germany clinical trials actively recruiting patients volunteers.

Found 403 clinical trials
H Hannes Gieseler

Troubled-Desire & Therapeutic Chat for Reduction of CSAM Use (TD-CHAT)

The goal of this prospective multicentred, stratified, parallel-group superiority study is to prevent and reduce the usage of Child Sexual Abuse Material (CSAM) by a Therapist Chat Service (TCS) and Selfhelp Platform for Self-Referred Patients, mostly men with a sexual interest in children. The interventions are based on Cognitive Behavioral …

18 - 99 years of age All Phase N/A
K Kerem Böge, Dr.

Efficacy of an Online-Based Self-Help Intervention for Auditory Hallucinations in Persons With Psychotic Disorders

The proposed clinical trial aims to examine the efficacy of an online-based self-help intervention for auditory hallucinations in persons with psychotic disorders. The intervention is primarily based on Metacognitive Training (MKT) and Mindfulness-Based Group Therapy (MBGT). The investigators will utilize a mixed-method study design within a randomized controlled trial. The …

18 - 75 years of age All Phase N/A
S Svenja Taubner, Prof.

Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany

Background: Borderline Personality Disorder (BPD) is a serious mental disorder. Mentalization-based treatment (MBT) is one evidence-based treatment for individuals with BPD. Specifically, MBT has been highlighted for its effectiveness in reduction of suicidal and non-suicidal self-injury (NSSI). Yet, randomized-controlled trials (RCT) on MBT in outpatient settings compared with bona fide …

18 - 65 years of age All Phase N/A
M Matthias Blüher, Prof. Dr.

SGLT2 Inhibition in Addition to Lifestyle Intervention and Risk for Complications in Subtypes of Patients With Prediabetes

More than 50% of patients with type 2 diabetes develop micro- and/or macrovascular complications during the course of the disease. Additionally, many patients at risk for diabetes develop metabolically driven complications including kidney and heart disease. Thus, it is of utmost importance to improve prevention of T2D and with this …

35 - 75 years of age All Phase 4
P Prof. Dr.

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

The aim of this prospective, randomized, controlled trial is to provide evidence for adjuvant IgGAM treatment with regard to Improvement of patient outcomes for peritonitis. Improvement in outcome will be determined by scores such as MOF, SOFA and survival. Identification of biomarkers (including immunoglobulin levels, HLA-DR, Nf-kB1 and other immunological …

18 years of age All Phase 2
L Larry Hinkson, FRCOG

Management of Retained Placenta With the "Windmill" Technique of Umbilical Cord Traction

The incidence of leftover placenta after vaginal delivery is between 0.1% and 3.3%, with a maternal mortality of up to 10% reported. The traditional management is ultimately the manual removal of the retained placenta (MROP) in the operating room. However, MROP itself increases the risk of further bleeding, postpartum infection, …

18 - 60 years of age Female Phase N/A

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female participants with DSWPD.

18 - 75 years of age All Phase 3

Exercise and Nutrition Intervention in Ovarian Cancer

The objective of this multicenter randomized controlled trial is to compare a 6-month exercise and nutrition intervention (intervention group, IG) aimed at maintaining or improving physical functioning and quality of life with usual care (control group, CG) in ovarian cancer patients. The main question it aims to answer is: • …

18 years of age Female Phase N/A

Intrapartum Ultrasound in Labor: Sonography Only, Few Internal Examinations

This is a prospective, randomized trial to determine whether the use of sonographic parameters during labor results in less intrapartum infection compared to traditional invasive examination. Other secondary outcomes include maternal satisfaction and overall birth outcomes.

18 - 60 years of age Female Phase N/A
E Ekaterina Nekhaeva, Dr.

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany. A total of 120 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight (BW) + standard of care versus same volume of placebo (NaCl) + standard of care.

18 years of age All Phase 2

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