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Brest Cedex 2, France Clinical Trials

A listing of Brest Cedex 2, France clinical trials actively recruiting patients volunteers.

Found 199 clinical trials
C Coralie Clodic, MD

Interest of Auriculotherapy in the Treatment of Xerostomia

The aim of the study is to show that auriculotherapy is effective in the treatment of xerostomia

18 years of age All Phase N/A
B Benjamin CHAIGNE, MD

Safety and Efficacy of Itacitinib in Adults With Systemic Sclerosis

The purpose of this study is to determine whether itacitinib is safe and effective in the treatment of systemic sclerosis in adults.

18 years of age All Phase 2
G Géraldine PAOLI-CAZANAVE

DVT Burden and the Risk of Post-thrombotic Syndrome

Post-thrombotic syndrome (PTS) is the most common chronic complication of deep vein thrombosis (DVT), with major consequences for patient quality of life and cost of management. Identifying patients at high risk of developing PTS could be useful for its prevention and may lead to more appropriate therapeutic strategies to reduce …

18 years of age All Phase N/A

Determinants of Repeated Spontaneous Miscarriages and Unexplained Fetal Deaths

The DEFI-1 study recruited 625 women witnesses and 299 of their spouses. With regard to case couples, 271 cases were recruited from the spontaneous repeated miscarriages (SRM) subgroup (≥3 spontaneous miscarriage (SM) from trimester 1 of pregnancy) and 93 from the unexplained fetal death in utero (FDIU) subgroup from trimesters …

18 - 40 years of age All Phase N/A
T Teresa Martinez

Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

This is a phase I/II study to assess safety, efficacy, and cellular kinetics of YTB323 in participants with treatment-resistant generalized myasthenia gravis. YTB323 is a Biological CAR-T cell therapy.

18 - 65 years of age All Phase 1/2
J Jacques Mansourati, Professor

Effect of Personalized Follow-up in Adapted Physical Activities in Subjects With Chronic Heart Failure.

France has one million people with heart failure (HF). Exercise intolerance, characterised by dyspnoea, is the main clinical symptom in HF patients and a key determinant of reduced quality of life. In addition to drug and surgical treatments, cardiac rehabilitation programmes have shown benefits in heart failure patients. Lasting at …

18 - 80 years of age All Phase N/A

Evaluation of the Valiant Captivia Physician Fenestrated Stent Graft System in Aortic Arch and Descending Thoracic Aorta Pathologies

The study objectives are to assess safety and effectiveness, measured acutely and at the 30-day visit after implantation of the Valiant Captivia physician fenestrated Stent Graft. Clinical utility measures throughout the procedure and until discharge will be assessed

18 years of age All Phase N/A
P Pascale TOMASINI, MD

Mechanisms of Resistance to Amivantamab in Patients With NSCLC With EGFR Exon 20 Insertion

The goal of this prospective, interventional study is to evaluate the mechanisms of acquired resistance to amivantamab monotherapy in patients with advanced NSCLC with EGFR ins20. The main question it aims to answer is: What are the mechanisms of acquired resistance to amivantamab monotherapy in this population of patients ? …

18 years of age All Phase N/A

Molecular Imaging of Active Venous Thrombus With Positron Emission Tomography (PET)

Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and/or pulmonary embolism (PE), is a major public health issue. VTE is the third most common acute cardiovascular pathology, after myocardial infarction and stroke. Diagnostic accuracy is essential in the case of VTE, in order to select patients for whom anticoagulant …

18 years of age All Phase N/A
V Vanessa SALIOU

Virtual Reality in Awake Surgery : Pilot Study VIRAS

The virtual reality mask is a tool likely to improve the conditions for performing awake surgery by improving tolerance for the patient, by improving ergonomics in the operating room. In order to control the risks as well as possible, the investigators propose to test the equipment on patients who will …

18 - 75 years of age All Phase N/A

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