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Koge, Denmark Clinical Trials

A listing of Koge, Denmark clinical trials actively recruiting patients volunteers.

Found 24 clinical trials

Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit.

This study evaluates the benefits and harms of goal directed fluid removal with furosemide versus placebo in critical ill adult patients with fluid overload in the intensive care unit. Half of the patients will receive furosemide and the other half placebo. The treatment will continue until the excess fluid is …

18 - 100 years of age Both Phase 4
S Steffen H Bruun, MD

Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With a Fracture

Aim: To compare the effect of one single dose versus multiple doses of prophylactic antibiotics administered within 24 hours, on the development of PJI after surgery in patients undergoing primary THA due to an acute fracture or sequelae of proximal femoral or acetabular fractures. The study is designed as a …

18 - 100 years of age Both Phase N/A
N Nanna Wagner Christiansen, B.Eng

Can Preoperative Information Via Virtual Reality Affect Patient's Anxiety?

The goal of this clinical trial is to test and learn about Virtual Reality (VR) providing preoperative information to patients undergoing elective TKA surgery in spinal anesthesia. The main question(s) aim(s) to answer if: Can preoperative information through a VR headset lower the patients preoperative anxiety? Can VR information make …

18 - 100 years of age Both Phase N/A
I Ismail Gögenur, Professor

The "SPARCOL" Study

Mortality following elective colorectal cancer surgery range between 2.5-6% and increase for the elderly and frail patient regardless of T-stage. Around 80% of the patients who present with a colon cancer and is in a condition where surgery is possible will be offered resection of the tumor. A part of …

65 - 100 years of age Both Phase N/A
S Sahar Moeini, MD

Inforatio Technique to Promote Wound Healing of Diabetic Foot Ulcers

This randomized clinical trial will examine the effect of inforatio technique on healing of diabetic foot ulcers (DFUs). Inforatio technique is a novel procedure developed by the research group. The definition of inforatio technique is application of small cuts in wound beds with punch biopsy tools without involving surrounding epithelia. …

18 - 100 years of age Both Phase N/A
P Peter Buxbom, MD, PhD

Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?

Treatment of displaced distal forearm fractures (DFF) in children have traditionally been closed reduction and pin fixation, although they might heal and remodel without manipulation, with no functional impairment. No randomized controlled trials (RCTs) have been published comparing the patient-reported functional outcome after non-surgical and surgical treatment of displaced DFF …

4 - 10 years of age Both Phase N/A

Early Initiated Vasopressor Therapy in the Emergency Department

The goal of this pragmatic, multi-center, superiority, randomized clinical trial is to compare early treatment with peripheral (through a vein) infused noradrenaline (a natural hormone that increases blood pressure) with fluid only therapy in patients with hypotensive and shock in the Danish Emergency Departments (ED). The main questions it aims …

18 - 100 years of age Both Phase 3
L Lars Christian Meyer, MD

A Randomized, Real-world Head-to-head Study of Dupilumab Versus Mepolizumab in Danish CRSwNP Patients

The goal of this randomized clinical trial is to compare the effects of two newly available biological drugs for the treatment of severe chronic rhinosinusitis with nasal polyps in Danish patients. The main questions it aims to answer are whether the two drugs are comparable in effect after 24 weeks …

18 - 100 years of age Both Phase 4

The DENOCHARCOT Trial

The aim of the present trial is to assess the efficacy of treatment of acute Charcot foot in diabetes patients with Prolia® on clinical relevant Outcomes in a randomized, double blind, placebo-controlled trial.

18 - 80 years of age Both Phase 3
C Clara Molin, MD

Fluid Administration and Fluid Accumulation in the Intensive Care Unit

The goal of this international inception cohort study is to describe fluid administration during admittance to the intensive care unit (ICU), and provide contemporary epidemiological data on fluid accumulation, risk factors, management and outcome in critically ill adult patients.

18 - 100 years of age Both Phase N/A

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