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Hlucin, Czech Republic Clinical Trials

A listing of Hlucin, Czech Republic clinical trials actively recruiting patients volunteers.

Found 81 clinical trials
J Jiří Hynčica

Biomarkers of Kidney Function in Transplant Medicine

Biomarkers of kidney function in transplant medicine is an international, multicentre, observational, non-interventional study. The project is aimed at monitoring biomarkers of acute kidney dysfunction in deceased organ donors, living organ donors, and organ recipients.

18 years of age All Phase N/A
E Eva Evinová, MD

Gastric Pathophysiology in Diabetes

This is a comprehensive pathophysiological study assessing various gastric functions in patients with diabetes mellitus. The investigators aim to examine the stomach with various measurement devices to gain information about its different functions and malfunctions. After the initial measurements, the examinations will be repeated after a year in each patient. …

18 - 70 years of age All Phase N/A
J Jiří Hynčica

Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients

Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin/creatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment. Modified human urine Fetuin A (urine Fetuin A) with specific modification in urine (Fetuin A) can earlier predict the progression of kidney disease in patients …

18 - 100 years of age All Phase N/A
M Milan Raška, prof.,MD,PhD

Early Diagnosis of Invasive Lung Aspergillosis

The last decade has seen a significant increase in secondary Aspergillus infections, not only due to primary hypersensitivity, and immunodeficiency based on oncological diseases and their therapy, but mainly due to a rise in severe respiratory infections (H1N1, COVID-19, bacterial infections). This is most evident in critically ill patients whose …

18 years of age All Phase N/A
J Jiří Hynčica

Invasive Candidiasis in Critical Care

The combination of acute phase marker monitoring and the "T2Candida" assay (name of the test) will represent an acceleration of the identification of the causative agent of mycotic infection, a significant improvement in the specificity and positive predictive value of this strategy in the diagnosis of invasive candidiasis and candidemia …

12 years of age All Phase N/A
J Jiří Hynčica

miRNA in Septic Acute Kidney Injury

Acute kidney injury is a common and serious complication of sepsis and septic shock, which may be associated with a worse outcome of the patient's condition. The exact pathophysiological mechanism of septic acute kidney injury remains a challenge. One of the possible causes appears to be endothelial dysfunction and mitochondrial …

18 - 100 years of age All Phase N/A
P Peter Ihnát, prof., MD, PhD, MBA

The Effect of Multimodal Treatment of Rectal Cancer on Circulating Tumor Cells: A Prospective, Observational Study

The prospective study will focus on patients undergoing multimodal treatment for rectal cancer. The main objective of the study will be to monitor changes in circulating tumor cells (CTCs) in the peripheral blood of patients during multimodal treatment. For each patient enrolled in the study, peripheral blood samples will be …

18 years of age All Phase N/A
R Roman Zachovál, prof., MD, PhD

Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients

This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendations for the treatment of overactive bladder (OAB). A portion of urine samples, which are routinely collected for biochemical and …

18 years of age Female Phase N/A
J Jiří Hynčica

The Effect of Autologous Hematopoietic Stem Cell Transplantation on the Lower Urinary Tract Function Related to QoL in MS Patients

Academic research project monitoring the effect of Autologous Hematopoietic Stem Cell Transplantation (AHSCT) on multiple sclerosis-associated lower urinary tract symptoms.

18 years of age All Phase N/A
J Jiří Hynčica

Adjustable Artificial Sphincter Victo in the Treatment of Male Incontinence Due to Prostate Surgery

The aim of this prospective academic research study is to evaluate the efficacy and safety of the Victo adjustable artificial sphincter in the treatment of male patients with urinary incontinence due to prostate surgery.

18 years of age Male Phase N/A

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