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Saint-Romuald, Canada Clinical Trials

A listing of Saint-Romuald, Canada clinical trials actively recruiting patients volunteers.

Found 373 clinical trials
P Patrick Richard, MD

A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer

This is a phase II randomized controlled clinical trial comparing standard induction BCG versus bicalutamide and standard induction BCG among patients with non-muscle invasive bladder cancer.

18 years of age Male Phase 2
E Emma Starr, BHSc

No Surgery Trial / Two Dose-escalation Strategies

A randomized study of 131 patients. Patients with a clinical T2-3 N0 rectal cancer will be randomized to two arms (arm A: standard chemoradiation (45 Gy in 25 with concomitant 5-FU or Xeloda chemotherapy) and an external beam boost of 9 Gy compared to arm B: standard chemoradiation (45 Gy …

18 - 80 years of age All Phase 2/3

Surveillance of Complex Renal Cysts - The SOCRATIC Study

One third of individuals aged \>60 years will be diagnosed with at least one renal cyst following abdominal imaging. These cystic lesions are categorized according to the Bosniak classification which categorizes cysts according to their degree of complexity and risk of malignancy. Growing evidence suggests that a significant proportion of …

18 years of age All Phase N/A

Radial Artery Occlusion and Dual Artery Hemostasis After Transradial Approach.

Improving patient comfort and implementing the protocols required to minimize the risk of RAO must be part of quality control. Several procedural parameters are related to the risk of RAO but hemostasis is a critical period. Despite the fact that non-occlusive hemostasis of the radial artery is a recognized and …

18 years of age All Phase N/A
M Melanie Cote

Frailty in Patient Undergoing Percutaneous Left Atrial Appendage Closure.

To assess the prevalence and severity of frailty in patients undergoing LAAC, as well as its association to peri-procedural and long-term outcomes and quality of life.

18 years of age All Phase N/A

Selective Early Medical Treatment of Patent Ductus Arteriosus in Extremely Low Gestational Age Infants: A Pilot RCT

Background: Among preterm infants, those born at a gestational age less than 26 weeks are considered the most vulnerable with a high risk of short- and long-term health problems that include chronic lung disease, brain bleeds, gut injury, kidney failure and death. Patent ductus arteriosus (PDA) is the most common …

- 72 years of age All Phase 3
S Site Public Contact

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with newly diagnosed or previously untreated low-grade glioma (LGG) that does not have a genetic abnormality called BRAFV600E mutation and is not associated with systemic neurofibromatosis type …

2 - 21 years of age All Phase 3

Serotonin Receptor Blockers in Ischemic Mitral Regurgitation

This study is intended to investigate the effect of cyproheptadine (a 5HT2B receptor blocker) on mitral regurgitation severity.

18 - 80 years of age All Phase 2

Comparing Hypothermic Temperatures During Hemiarch Surgery

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral organs, but may result in longer cardiopulmonary bypass times during surgery, increased risks of bleeding, inflammation, and neuronal injury. To manage these consequences, a trend …

18 years of age All Phase N/A
M Marie-Christine Dube, PhD

Personalized vs. Fixed-Activity 177Lu-PSMA-617 Radiopharmaceutical Therapy (PRODIGY-2)

The goal of this clinical trial is to assess if a personalized regime of 177Lu-PSMA-617 (Lutetium Lu 177 vipivotide tetraxetan, also known as Pluvicto) is feasible and safe in a population of patients with metastatic castrate-resistant prostate cancer (mCRPC). The main questions it aims to answer are: Can the administered …

18 years of age Male Phase 1

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