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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials

A Study to Evaluate the Safety, Tolerability, PK and PD of AP303 in DKD Patients

The study will be a single center, double-blind, randomized, placebo-controlled study to evaluate the safety, tolerability, PK and PD of AP303 following 2-week oral administration to Diabetic Kidney Disease patients.

30 years of age All Phase 1
E Evelyn Monninkhof, PhD

The Effect of a Combined Lifestyle Intervention for Patients With Cancer on Quality of Life

A growing number of people are living with the (long-term) consequences of cancer and its treatment, which can negatively affect their quality of life. This study aims to assess the effect of a combined lifestyle intervention for patients with cancer on quality of life.

40 years of age All Phase N/A
Z Zheng Professor

To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension

This is a prospective, multicenter, blinded, randomized controlled clinical trial designed to evaluate the safety and efficacy of a single-use intravascular ultrasound ablation catheter and ultrasound ablation system in the treatment of primary hypertension.

18 - 75 years of age All Phase N/A
L Loree Brennan O'Jack, CPA, MHSA

Neurobehavioral Signatures of Sign- and Goal-Tracking in Emerging Adults: Translation of a Preclinical Model

This study seeks to understand individual differences in personality, brain function, and behavior. Study hypothesis: A stronger sign-tracking bias will be associated with a bottom-up processing style characterized by less adaptive attentional- and impulse-control as well as hyperactive reward processing, whereas a stronger goal-tracking bias will be associated with a …

18 - 20 years of age All Phase N/A
A Astrid POZET

Evolution of Vestibular Function After Treatment of a Vestibular Schwannoma by Gamma-knife Radio-surgery

The purpose of this study is to evaluate the vestibular effects of gamma-knife radiosurgery, as part of the treatment of vestibular schwannoma.

18 - 90 years of age All Phase N/A
V Viktoria Dedkova, MD

Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers

This study aims to evaluate the safety, tolerability, and pharmacokinetic profile of the Grammidin, a metered dose topical spray, compared to Grammidin lozenges following single administration in healthy volunteers .

18 - 45 years of age All Phase 1
M Monica Ulles

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

This is a Phase 1/2 multicenter, open-label, single dose trial of SP-101 investigational gene therapy in adults with CF who are ineligible for or intolerant to CFTR modulator therapy.

18 - 65 years of age All Phase 1/2
M Megan Lau

A Qualitative and Usability Evaluation of Advanced Technologies for Home Upper Limb Neurorehabilitation Post-stroke

Due to limited resources such as the low therapist to patient ratio or high costs associated to rehabilitation therapy, providing higher therapy dose to patients after discharge is highly challenging. This often results in non-use of the impaired limb as a result of the decreased therapy dose, causing partial loss …

21 - 80 years of age All Phase N/A
K Kara Hoffman

A Phase II Study of ACR-368 and Low Dose Gemcitabine in R/M HNSCC

The purpose of the study is to determine the activity and safety of ACR-368 (prexasertib) in combination with gemcitabine in participants with Head and Neck Squamous Cell Carcinoma (HNSCC). Participants will receive the study drugs ACR-368 and a low dose of gemcitabine once every 2 weeks in 4-week cycles and …

18 years of age All Phase 2
F Fang Zhao, MD

Safety and Efficacy of Using a Novel Full Visual Access Platform System in Transvaginal Hysterectomy

The modified vNOTES hysterectomy was accomplished and validated for efficacy and safety using a multi-access vaginal confinement instrument with a fully visualised vaginal access platform.

- 60 years of age Female Phase N/A

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