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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials
M Meg Thomas

A Study of Valemetostat Tosylate (DS-3201b) With Atezolizumab and Bevacizumab in HCC

This is a phase Ib/II, dose escalation and dose expansion study of valemetostat (DS-3201) with atezolizumab and bevacizumab in patients advanced Hepatocellular carcinoma (HCC) who did not receive prior systemic therapy for advanced HCC.

18 years of age All Phase 1/2

Resveratrol-Based Gel Application in a Palatal Wound Following Free Gingival Graft Surgery

Aim of the study to compare the effect of Resveratrol- Based gel versus 0.2% Hyaluronic acid gel applied to the palatal donor site and acrylic resin stent only in post-operative pain reduction after free gingival graft harvesting.

18 years of age All Phase N/A
S Sarah Jackson, PhD

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

The purpose of this study is to demonstrate the feasibility and utility of SIT delivered asynchronously (self-paced) via fully virtual platform with and without the aid of a mobile health application and to determine initial change over baseline in terms of reduction in PTSD symptoms and improvement in resiliency in …

18 - 79 years of age All Phase N/A

A Study of BL-M08D1 in Patients With Relapsed or Refractory Lymphoid Malignancies

This study is an open-label, multicenter, dose-escalation and extended-enrollment, nonrandomized phase I study to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of BL-M08D1 for injection in relapsed or refractory lymphoid malignancies.

18 - 75 years of age All Phase 1

Reducing Cognitive Impairment by Management of Heart Failure as a Modifiable Risk Factor

This study will test the feasibility and effectiveness of an innovative model of care for cognitively impaired patients with heart failure. This program aims to improve cognition, reduce dementia risk and cardiovascular events, and will be supported by innovative digital technology for wide scale rollout and implementation. Findings from this …

18 years of age All Phase N/A
C Christina C Chang, phD

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of RSN0402 in Healthy Volunteers

This is a phase 1, randomized, First in Human (FIH), double-blinded, placebo-controlled study to assess the safety, tolerability, and PK of RSN0402 in healthy volunteers. A total of about 72 participants are expected to be enrolled.

18 - 60 years of age All Phase 1
M Maryam Rahat, Ph.D Candidate

Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study

Cannabis is the most commonly used psychoactive substance in Canada (Lowry & Corsi, 2020). A sub-group of cannabis users develop a condition known as Cannabis Use Disorder (CUD), which is defined as a regular pattern of cannabis use that causes performance difficulty at work, school and relationships (Hasin et al., …

18 - 65 years of age All Phase 2
C Changsheng Ma

A Clinical Study of MT1002 in Subjects With Acute Coronary Syndrome Undergoing PCI

An Open-label, Sequential Dose Escalation/De-escalation Clinical Trial of MT1002 in Subjects With Acute Coronary Syndrome Undergoing PCI.

18 - 85 years of age All Phase 2
M Melissa L Anderson, PhD

Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma

The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure compared to the general population. Although there are several treatments for alcohol use …

18 years of age All Phase N/A
Q Qing Fan, Doctor

Effect of a Family-Based CBT Self-Help Intervention for Adolescents With OCD

The goal of this clinical trial is to learn if self-help book can be used to treat obsessive-compulsive disorder (OCD) in adolescents aged 10 to 17. The main questions it aims to answer are: Can adolescents and their parents effectively reduce the severity of the obsessive-compulsive symptoms in adolescents who …

10 - 17 years of age All Phase N/A

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