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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,120 clinical trials

Interferon-gamma as Adjunctive Therapy in Chronic Pulmonary Aspergillosis: a Randomised Feasibility Study

This study explores the role of treatment with interferon-gamma to improve outcomes in chronic pulmonary aspergillosis (CPA). CPA is a progressive infection caused by the fungus Aspergillus affecting patients with chronic lung disease like Chronic Obstructive Lung Disease (COPD) or previously treated tuberculosis (TB). It causes gradual destruction of lung …

18 years of age All Phase 2

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

The primary objectives of this study are to assess the efficacy of TB006 in improving motor function and to assess the safety of TB006 in participants with Parkinson's Disease (PD).

50 - 80 years of age All Phase 2
G Gisela Jimenez-Colon, PhD

A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior

This study will test a model of providing treatment to Latinx/Hispanic youth, who experience suicidal thoughts and behavior, and their caregivers. An affirmative and culturally relevant treatment will be provided to all youth and half of the families will be assigned to the additional support of a community health worker …

12 - 18 years of age All Phase N/A
P Peter R Chai, MD, MMS

A Single-Dose, Three-Way, Three-Sequence, Crossover BA Study of Azithromycin Oleogel

This is an exploratory study to describe the pharmacokinetics of the azithromycin oral and rectal oleogel in humans compared to the reference oral drug to (Zithromax) assess the impact of the novel formulation on bioavailability. The investigators will perform a randomized, balanced, single dose, three-treatment, three-period, crossover oral bioavailability study …

18 - 45 years of age All Phase 1
B Beth Thomsen

A Phase I Trial of 61Cu-NODAGA-PSMA for Patients with Prostate Cancer

Molecular Imaging (MI) uses tracers which emit radiation to provide clinically valuable imaging for patient with cancer. Most current MI agents utilize Fluorine 18 or Gallium 68 as the positron emitter for PET imaging. However, these isotopes have short half-lives which limit the geographic distribution range of tracers made with …

18 years of age Male Phase 1
J JBR Patient Inquiries

A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction

The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extraction. The main questions the study will answer are: How much of the investigational product is absorbed in the blood? Are there side effects?

18 - 55 years of age All Phase N/A

A Trial of HRS-1358 Tablets in Metastatic or Local Advanced Breast Cancer

The study is being conducted to evaluate the safety and tolerability of HRS-1358 monotherapy or combination with Dalpiciclib Isethionate Tablets in patients with metastatic or locally advanced breast cancer in order to estimate the Dose-Limiting Toxicity (DLT), Maximum Tolerated Dose (MTD) and select the Recommended Phase 2 Dose (RP2D).

18 - 75 years of age Female Phase 1
Y Yuankai Shi, MD

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of YK012

This study aims to provide a basis for further clinical development of YK012.

18 - 65 years of age All Phase 1

Assessing the Efficacy of a Preoperative Navigation System in Anterior Cruciate Ligament Reconstruction

The ACL surgery robot features a preoperative navigation system that enhances the precision of bone tunnel placement. As the first dual-bundle reconstruction surgical robot developed in China, it integrates advanced technology to ensure accurate anatomical alignment. This multi-center study aims to evaluate the robot's effectiveness in improving surgical outcomes and …

18 - 80 years of age All Phase N/A

A Clinical Study of SPH7485 Tablets in the Treatment of Advanced Solid Tumors.

To evaluate the efficacy and safety of SPH7485 tablets in patients with advanced solid tumors.

18 - 75 years of age All Phase 1

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